Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes REEP6
  • Mouse genes Reep6
  • Rat genes Reep6
  • Zfish genes reep6,zgc:101744
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Reep6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	REEP6	IPI	UniProtKB:Q8N612	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	REEP6	IPI	UniProtKB:Q9NRS6	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	REEP6	IPI	UniProtKB:Q13596	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	REEP6	IPI	UniProtKB:O00560	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	REEP6	IPI	UniProtKB:Q13596	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	REEP6	IPI	UniProtKB:Q63HR2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	REEP6	IPI	UniProtKB:Q6IQ43	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	REEP6	IPI	UniProtKB:Q6NT76	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	REEP6	IPI	UniProtKB:Q6NT76-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	REEP6	IPI	UniProtKB:Q8N612	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	REEP6	IPI	UniProtKB:Q8NI60	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	REEP6	IPI	UniProtKB:Q99732	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	REEP6	IPI	UniProtKB:Q99757	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	REEP6	IPI	UniProtKB:Q9BQ24	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	REEP6	IPI	UniProtKB:Q9NRS6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	REEP6	IPI	UniProtKB:Q9NZD8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	REEP6	IPI	UniProtKB:Q8NI60	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	REEP6	IPI	UniProtKB:Q99732	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	REEP6	IPI	UniProtKB:Q8NI60	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	REEP6	IPI	UniProtKB:Q99732	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	REEP6	IPI	UniProtKB:Q9NRS6	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	REEP6	IPI	UniProtKB:Q9NZD8	Human	PMID:31515488
Cellular Component	GO:0045177	apical part of cell	Reep6	IDA		Mouse	PMID:23284756
Cellular Component	GO:0005783	endoplasmic reticulum	REEP6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	REEP6	IDA		Human	PMID:27889058
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Reep6	IDA		Mouse	MGI:MGI:5578015|PMID:24098485
Cellular Component	GO:0005634	nucleus	REEP6	HDA		Human	PMID:21630459
Cellular Component	GO:0001917	photoreceptor inner segment	REEP6	IDA		Human	PMID:27889058
Cellular Component	GO:0044317	rod spherule	Reep6	IDA		Mouse	MGI:MGI:5582989|PMID:24691551
Biological Process	GO:0050908	detection of light stimulus involved in visual perception	REEP6	IMP		Human	PMID:27889058
Biological Process	GO:0060059	embryonic retina morphogenesis in camera-type eye	reep6	IMP		Zfish	PMID:24691551|ZFIN:ZDB-PUB-140513-225
Biological Process	GO:0032386	regulation of intracellular transport	Reep6	IDA		Mouse	MGI:MGI:5578015|PMID:24098485
Biological Process	GO:0010842	retina layer formation	reep6	IMP		Zfish	PMID:24691551|ZFIN:ZDB-PUB-140513-225
Biological Process	GO:0010842	retina layer formation	reep6	IMP	ZFIN:ZDB-MRPHLNO-170817-7	Zfish	PMID:24691551
Biological Process	GO:0010842	retina layer formation	reep6	IMP	ZFIN:ZDB-MRPHLNO-170817-6	Zfish	PMID:24691551

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern