Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RASIP1
  • Mouse genes Rasip1
  • Rat genes Rasip1
  • Zfish genes rasip1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rasip1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051020	GTPase binding	RASIP1	IPI	UniProtKB:P61224	Human	PMID:26780829
Molecular Function	GO:0005515	protein binding	RASIP1	IPI	UniProtKB:E9Q7X6	Human	PMID:26780829
Molecular Function	GO:0005515	protein binding	RASIP1	IPI	UniProtKB:Q9ULI3	Human	PMID:26780829
Molecular Function	GO:0005515	protein binding	Rasip1	IPI	UniProtKB:Q8CGF1|UniProtKB:Q8VDD5	Mouse	MGI:MGI:5052000|PMID:21396893
Molecular Function	GO:0042803	protein homodimerization activity	RASIP1	IDA		Human	PMID:26780829
Cellular Component	GO:0005911	cell-cell junction	RASIP1	IMP		Human	PMID:26780829
Cellular Component	GO:0032991	protein-containing complex	RASIP1	IDA		Human	PMID:26780829
Biological Process	GO:0001525	angiogenesis	Rasip1	IMP		Mouse	MGI:MGI:3844403|PMID:19272373
Biological Process	GO:0048754	branching morphogenesis of an epithelial tube	Rasip1	IMP		Mouse	MGI:MGI:5052000|PMID:21396893
Biological Process	GO:0045216	cell-cell junction organization	rasip1	IMP	ZFIN:ZDB-GENO-230104-2	Zfish	PMID:34383884
Biological Process	GO:0010507	negative regulation of autophagy	RASIP1	IMP		Human	PMID:22354037
Biological Process	GO:1905709	negative regulation of membrane permeability	RASIP1	IDA		Human	PMID:26780829
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	RASIP1	IMP		Human	PMID:26780829
Biological Process	GO:2000299	negative regulation of Rho-dependent protein serine/threonine kinase activity	RASIP1	IMP		Human	PMID:26780829
Biological Process	GO:0033625	positive regulation of integrin activation	RASIP1	IMP		Human	PMID:26780829
Biological Process	GO:0043087	regulation of GTPase activity	Rasip1	IMP		Mouse	MGI:MGI:5052000|PMID:21396893
Biological Process	GO:0002040	sprouting angiogenesis	rasip1	IMP	ZFIN:ZDB-GENO-230104-2	Zfish	PMID:34383884
Biological Process	GO:0001944	vasculature development	rasip1	IMP	ZFIN:ZDB-MRPHLNO-140128-2	Zfish	PMID:23886837
Biological Process	GO:0001944	vasculature development	rasip1	IMP	ZFIN:ZDB-MRPHLNO-140127-1	Zfish	PMID:23886837
Biological Process	GO:0001570	vasculogenesis	Rasip1	IMP		Mouse	MGI:MGI:5052000|PMID:21396893

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern