Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTPA
  • Mouse genes Ptpa
  • Rat genes Ptpa
  • Zfish genes ptpa
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptpa

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	PTPA	IDA		Human	PMID:16916641
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	PTPA	IDA		Human	PMID:16916641
Molecular Function	GO:0005515	protein binding	PTPA	IPI	UniProtKB:Q4VCS5-2	Human	PMID:25416956
Molecular Function	GO:0042803	protein homodimerization activity	PTPA	IDA		Human	PMID:16916641
Molecular Function	GO:0051721	protein phosphatase 2A binding	PTPA	IDA		Human	PMID:16916641
Molecular Function	GO:0019888	protein phosphatase regulator activity	PTPA	IDA		Human	PMID:16916641
Molecular Function	GO:0008160	protein tyrosine phosphatase activator activity	PTPA	IDA		Human	PMID:16916641
Molecular Function	GO:0005102	signaling receptor binding	PTPA	IPI	UniProtKB:Q92736	Human	PMID:10830164
Cellular Component	GO:1904949	ATPase complex	PTPA	IDA		Human	PMID:16916641
Cellular Component	GO:0034704	calcium channel complex	PTPA	IDA		Human	PMID:10830164
Cellular Component	GO:0005737	cytoplasm	PTPA	IDA		Human	PMID:17333320
Cellular Component	GO:0070062	extracellular exosome	PTPA	HDA		Human	PMID:23533145
Cellular Component	GO:0005654	nucleoplasm	PTPA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PTPA	IDA		Human	PMID:17333320
Cellular Component	GO:0000159	protein phosphatase type 2A complex	PTPA	IDA		Human	PMID:10318862
Biological Process	GO:0032515	negative regulation of phosphoprotein phosphatase activity	PTPA	IDA		Human	PMID:16916641
Biological Process	GO:0035308	negative regulation of protein dephosphorylation	PTPA	IDA		Human	PMID:16916641
Biological Process	GO:0043065	positive regulation of apoptotic process	PTPA	IDA		Human	PMID:17333320
Biological Process	GO:0032516	positive regulation of phosphoprotein phosphatase activity	PTPA	IDA		Human	PMID:16916641
Biological Process	GO:0035307	positive regulation of protein dephosphorylation	PTPA	IDA		Human	PMID:16916641
Biological Process	GO:0043666	regulation of phosphoprotein phosphatase activity	PTPA	IDA		Human	PMID:16916641

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern