Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRIMPOL
  • Mouse genes Primpol
  • Rat genes Primpol
  • Zfish genes primpol
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Primpol

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	PRIMPOL	IDA		Human	PMID:24240614
Molecular Function	GO:0003682	chromatin binding	PRIMPOL	IDA		Human	PMID:28534480
Molecular Function	GO:0003896	DNA primase activity	PRIMPOL	IDA		Human	PMID:24207056
Molecular Function	GO:0003896	DNA primase activity	PRIMPOL	IDA		Human	PMID:24240614
Molecular Function	GO:0003896	DNA primase activity	PRIMPOL	IDA		Human	PMID:24267451
Molecular Function	GO:0003896	DNA primase activity	PRIMPOL	IDA		Human	PMID:24682820
Molecular Function	GO:0003896	DNA primase activity	PRIMPOL	IDA		Human	PMID:28534480
Molecular Function	GO:0003896	DNA primase activity	PRIMPOL	IDA		Human	PMID:29608762
Molecular Function	GO:0003896	DNA primase activity	PRIMPOL	IDA		Human	PMID:30478192
Molecular Function	GO:0003896	DNA primase activity	Primpol	IDA		Mouse	MGI:MGI:6393030|PMID:29073063
Molecular Function	GO:0003887	DNA-directed DNA polymerase activity	PRIMPOL	IDA		Human	PMID:24207056
Molecular Function	GO:0003887	DNA-directed DNA polymerase activity	PRIMPOL	IDA		Human	PMID:25746449
Molecular Function	GO:0030145	manganese ion binding	PRIMPOL	IDA		Human	PMID:25746449
Molecular Function	GO:0005515	protein binding	PRIMPOL	IPI	UniProtKB:P27694	Human	PMID:24126761
Molecular Function	GO:0005515	protein binding	PRIMPOL	IPI	UniProtKB:P27694	Human	PMID:28534480
Molecular Function	GO:0005515	protein binding	PRIMPOL	IPI	UniProtKB:P25786	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRIMPOL	IPI	UniProtKB:P55273	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRIMPOL	IPI	UniProtKB:Q00013	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRIMPOL	IPI	UniProtKB:Q8NEY1-3	Human	PMID:32296183
Molecular Function	GO:0008270	zinc ion binding	PRIMPOL	IDA		Human	PMID:24682820
Cellular Component	GO:0005759	mitochondrial matrix	PRIMPOL	IDA		Human	PMID:24207056
Cellular Component	GO:0005634	nucleus	PRIMPOL	IDA		Human	PMID:24207056
Cellular Component	GO:0005634	nucleus	PRIMPOL	IDA		Human	PMID:24240614
Cellular Component	GO:0005657	replication fork	PRIMPOL	IDA		Human	PMID:28534480
Biological Process	GO:0042276	error-prone translesion synthesis	PRIMPOL	IDA		Human	PMID:24682820
Biological Process	GO:0042276	error-prone translesion synthesis	PRIMPOL	IDA		Human	PMID:25746449
Biological Process	GO:0042276	error-prone translesion synthesis	PRIMPOL	IDA		Human	PMID:28534480
Biological Process	GO:0043504	mitochondrial DNA repair	Primpol	IDA		Mouse	MGI:MGI:6393030|PMID:29073063
Biological Process	GO:0006264	mitochondrial DNA replication	PRIMPOL	IMP		Human	PMID:24207056
Biological Process	GO:0006264	mitochondrial DNA replication	Primpol	IMP		Mouse	MGI:MGI:5527006|PMID:24207056
Biological Process	GO:0062176	R-loop processing	PRIMPOL	IDA		Human	PMID:30478192
Biological Process	GO:0031297	replication fork processing	PRIMPOL	IMP		Human	PMID:24240614
Biological Process	GO:0031297	replication fork processing	PRIMPOL	IMP		Human	PMID:24267451
Biological Process	GO:0031297	replication fork processing	PRIMPOL	IDA		Human	PMID:28534480
Biological Process	GO:0009411	response to UV	PRIMPOL	IDA		Human	PMID:24240614
Biological Process	GO:0009411	response to UV	PRIMPOL	IDA		Human	PMID:24267451
Biological Process	GO:0019985	translesion synthesis	PRIMPOL	IMP		Human	PMID:24240614
Biological Process	GO:0019985	translesion synthesis	PRIMPOL	IMP		Human	PMID:24267451

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern