Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRG3
  • Mouse genes Prg3
  • Rat genes Prg3
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prg3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030021	extracellular matrix structural constituent conferring compression resistance	PRG3	HDA		Human	PMID:28344315
Cellular Component	GO:0062023	collagen-containing extracellular matrix	PRG3	HDA		Human	PMID:28344315
Cellular Component	GO:0062023	collagen-containing extracellular matrix	PRG3	HDA		Human	PMID:25037231
Biological Process	GO:0045575	basophil activation	PRG3	IDA		Human	PMID:10318872
Biological Process	GO:0001694	histamine biosynthetic process	PRG3	IDA		Human	PMID:10318872
Biological Process	GO:0019370	leukotriene biosynthetic process	PRG3	IDA		Human	PMID:10318872
Biological Process	GO:0017148	negative regulation of translation	PRG3	IDA		Human	PMID:10318872
Biological Process	GO:0042119	neutrophil activation	PRG3	IDA		Human	PMID:10318872
Biological Process	GO:0032757	positive regulation of interleukin-8 production	PRG3	IDA		Human	PMID:10318872
Biological Process	GO:0042554	superoxide anion generation	PRG3	IDA		Human	PMID:10318872

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern