Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PPP4R4
  • Mouse genes Ppp4r4
  • Rat genes Ppp4r4
  • Zfish genes ppp4r4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ppp4r4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PPP4R4	IPI	UniProtKB:P60510	Human	PMID:18715871
Molecular Function	GO:0005515	protein binding	PPP4R4	IPI	UniProtKB:P60510	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	PPP4R4	IPI	UniProtKB:P60510	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	Ppp4r4	IPI	PR:P97470	Mouse	PMID:18715871
Molecular Function	GO:0019888	protein phosphatase regulator activity	PPP4R4	IDA		Human	PMID:18715871
Cellular Component	GO:0005737	cytoplasm	PPP4R4	IDA		Human	PMID:18715871
Cellular Component	GO:0005829	cytosol	PPP4R4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0008287	protein serine/threonine phosphatase complex	PPP4R4	IDA		Human	PMID:18715871
Biological Process	GO:0001835	blastocyst hatching	Ppp4r4	IMP		Mouse	PMID:27869233
Biological Process	GO:0032515	negative regulation of phosphoprotein phosphatase activity	PPP4R4	IDA		Human	PMID:18715871
Biological Process	GO:0080163	regulation of protein serine/threonine phosphatase activity	PPP4R4	IDA		Human	PMID:18715871

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern