Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PPP3R2
  • Mouse genes Ppp3r2
  • Rat genes Ppp3r2
  • Zfish genes ppp3r1a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ppp3r2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity	PPP3R2	IDA		Human	PMID:26429887
Molecular Function	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity	Ppp3r2	IMP	MGI:MGI:5788176	Mouse	PMID:26429887
Molecular Function	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity	Ppp3r2	IDA		Mouse	PMID:26429887
Molecular Function	GO:0005515	protein binding	PPP3R2	IPI	UniProtKB:Q12800	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PPP3R2	IPI	UniProtKB:Q96N06	Human	PMID:34446558
Molecular Function	GO:0005515	protein binding	Ppp3r2	IPI	UniProtKB:Q8C624	Mouse	MGI:MGI:6758705|PMID:34446558
Molecular Function	GO:0005515	protein binding	Ppp3r2	IPI	RGD:620103	Rat	PMID:15120593|RGD:1579942
Cellular Component	GO:0005955	calcineurin complex	Ppp3r2	IDA		Mouse	PMID:1325794
Cellular Component	GO:0005955	calcineurin complex	Ppp3r2	IDA		Mouse	PMID:26429887
Cellular Component	GO:0005955	calcineurin complex	Ppp3r2	IGI	MGI:MGI:107162	Mouse	PMID:26429887
Cellular Component	GO:0036126	sperm flagellum	Ppp3r2	IDA		Mouse	PMID:26429887
Cellular Component	GO:0097225	sperm midpiece	Ppp3r2	IDA		Mouse	MGI:MGI:6758705|PMID:34446558
Cellular Component	GO:0097226	sperm mitochondrial sheath	Ppp3r2	IDA		Mouse	PMID:34446558
Biological Process	GO:0007341	penetration of zona pellucida	Ppp3r2	IMP	MGI:MGI:5788176	Mouse	PMID:26429887

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern