Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes POLR2C
  • Mouse genes Polr2c
  • Rat genes Polr2c
  • Zfish genes polr2c
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Polr2c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	POLR2C	IPI	UniProtKB:P18848	Human	PMID:12860379
Molecular Function	GO:0005515	protein binding	Polr2c	IPI	PR:Q8K2I2	Mouse	PMID:16141233
Molecular Function	GO:0005515	protein binding	Polr2c	IPI	PR:O08740	Mouse	PMID:9034305
Cellular Component	GO:0005737	cytoplasm	Polr2c	IDA		Mouse	PMID:16141233
Cellular Component	GO:0005829	cytosol	POLR2C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	POLR2C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	POLR2C	IDA		Human	PMID:9852112
Cellular Component	GO:0005634	nucleus	Polr2c	IDA		Mouse	PMID:16141233
Cellular Component	GO:0005665	RNA polymerase II, core complex	POLR2C	IDA		Human	PMID:9852112
Biological Process	GO:0006366	transcription by RNA polymerase II	POLR2C	IDA		Human	PMID:9852112

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern