Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes POLH
  • Mouse genes Polh
  • Rat genes Polh
  • Zfish genes polh
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Polh

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003887	DNA-directed DNA polymerase activity	Polh	IDA		Mouse	PMID:10871396
Molecular Function	GO:0005515	protein binding	POLH	IPI	UniProtKB:P0CG48	Human	PMID:16763556
Molecular Function	GO:0005515	protein binding	POLH	IPI	UniProtKB:Q6FI35	Human	PMID:16763556
Molecular Function	GO:0005515	protein binding	POLH	IPI	UniProtKB:P0CG48	Human	PMID:17304240
Molecular Function	GO:0005515	protein binding	POLH	IPI	UniProtKB:P51587	Human	PMID:24485656
Molecular Function	GO:0005515	protein binding	POLH	IPI	UniProtKB:Q86YC2	Human	PMID:24485656
Cellular Component	GO:0005829	cytosol	POLH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	POLH	IDA		Human	GO_REF:0000052
Biological Process	GO:0071494	cellular response to UV-C	Polh	IGI	MGI:MGI:1347081	Mouse	PMID:17114294
Biological Process	GO:0071494	cellular response to UV-C	Polh	IMP	MGI:MGI:3614412	Mouse	PMID:17114294
Biological Process	GO:0000731	DNA synthesis involved in DNA repair	POLH	IDA		Human	PMID:17563354
Biological Process	GO:0006301	postreplication repair	Polh	IDA		Mouse	PMID:10871396
Biological Process	GO:0006290	pyrimidine dimer repair	Polh	IDA		Mouse	PMID:10871396
Biological Process	GO:0010225	response to UV-C	POLH	IDA		Human	PMID:17563354

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern