Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PNPLA6
  • Mouse genes Pnpla6
  • Rat genes Pnpla6
  • Zfish genes pnpla6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pnpla6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004622	lysophospholipase activity	PNPLA6	EXP		Human	PMID:12514188
Molecular Function	GO:0004622	lysophospholipase activity	PNPLA6	EXP		Human	PMID:15044461
Molecular Function	GO:0004622	lysophospholipase activity	Pnpla6	IDA		Mouse	MGI:MGI:5770070|PMID:18086666
Cellular Component	GO:0005829	cytosol	PNPLA6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	PNPLA6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	PNPLA6	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Pnpla6	IDA		Mouse	MGI:MGI:5770070|PMID:18086666
Biological Process	GO:0001525	angiogenesis	Pnpla6	IMP	MGI:MGI:3028797	Mouse	PMID:14749382
Biological Process	GO:0009887	animal organ morphogenesis	Pnpla6	IMP	MGI:MGI:3028797	Mouse	PMID:14749382
Biological Process	GO:0009948	anterior/posterior axis specification	pnpla6	IMP	ZFIN:ZDB-MRPHLNO-130516-8	Zfish	PMID:22996643
Biological Process	GO:0007409	axonogenesis	pnpla6	IMP	ZFIN:ZDB-MRPHLNO-130516-8	Zfish	PMID:22996643
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	pnpla6	IMP	ZFIN:ZDB-MRPHLNO-130516-8	Zfish	PMID:22996643
Biological Process	GO:0048666	neuron development	pnpla6	IMP	ZFIN:ZDB-MRPHLNO-130516-8	Zfish	PMID:22996643

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern