Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PNKD
  • Mouse genes Pnkd
  • Rat genes Pnkd
  • Zfish genes pnkd
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pnkd

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PNKD	IPI	UniProtKB:P27361	Human	PMID:25066297
Molecular Function	GO:0005515	protein binding	PNKD	IPI	UniProtKB:P43364-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PNKD	IPI	UniProtKB:Q7L273	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PNKD	IPI	UniProtKB:G5E962	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	Pnkd	IPI	PR:Q99NE5	Mouse	PMID:25730884
Molecular Function	GO:0005515	protein binding	Pnkd	IPI	PR:Q9EQZ7	Mouse	PMID:25730884
Cellular Component	GO:0016020	membrane	PNKD	IDA		Human	PMID:22214848
Cellular Component	GO:0005739	mitochondrion	PNKD	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Pnkd	HDA		Mouse	PMID:18614015
Cellular Component	GO:0099523	presynaptic cytosol	Pnkd	IDA		Mouse	PMID:25730884
Biological Process	GO:0046929	negative regulation of neurotransmitter secretion	PNKD	IMP		Human	PMID:25730884
Biological Process	GO:0046929	negative regulation of neurotransmitter secretion	Pnkd	IGI	MGI:MGI:2152971	Mouse	PMID:25730884
Biological Process	GO:0046929	negative regulation of neurotransmitter secretion	Pnkd	IGI	MGI:MGI:2152972	Mouse	PMID:25730884
Biological Process	GO:0050884	neuromuscular process controlling posture	Pnkd	IMP	MGI:MGI:5006973	Mouse	PMID:22214848
Biological Process	GO:0042053	regulation of dopamine metabolic process	Pnkd	IMP	MGI:MGI:5006973	Mouse	PMID:22214848
Biological Process	GO:0032225	regulation of synaptic transmission, dopaminergic	Pnkd	IMP	MGI:MGI:5006973	Mouse	PMID:22214848

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern