Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLXNB1
  • Mouse genes Plxnb1
  • Rat genes Plxnb1
  • Zfish genes plxnb1a,plxnb1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plxnb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0032794	GTPase activating protein binding	Plxnb1	IPI	UniProtKB:Q7TQK9|UniProtKB:Q8R4H2	Mouse	MGI:MGI:5297297|PMID:22019888
Molecular Function	GO:0005515	protein binding	PLXNB1	IPI	UniProtKB:Q92730	Human	PMID:12730235
Molecular Function	GO:0005515	protein binding	PLXNB1	IPI	UniProtKB:P61587	Human	PMID:14732713
Molecular Function	GO:0005515	protein binding	PLXNB1	IPI	UniProtKB:Q92730	Human	PMID:14732713
Molecular Function	GO:0005515	protein binding	PLXNB1	IPI	UniProtKB:P08581	Human	PMID:15184888
Molecular Function	GO:0005515	protein binding	PLXNB1	IPI	UniProtKB:Q04912	Human	PMID:15184888
Molecular Function	GO:0005515	protein binding	PLXNB1	IPI	UniProtKB:Q92854	Human	PMID:15218527
Molecular Function	GO:0005515	protein binding	PLXNB1	IPI	UniProtKB:P10301	Human	PMID:19843518
Molecular Function	GO:0005515	protein binding	PLXNB1	IPI	UniProtKB:P63000	Human	PMID:19843518
Molecular Function	GO:0005515	protein binding	PLXNB1	IPI	UniProtKB:Q92730	Human	PMID:19843518
Molecular Function	GO:0005515	protein binding	PLXNB1	IPI	UniProtKB:Q92854	Human	PMID:20877282
Molecular Function	GO:0005515	protein binding	PLXNB1	IPI	UniProtKB:P08581	Human	PMID:22404908
Molecular Function	GO:0005515	protein binding	PLXNB1	IPI	UniProtKB:P52198	Human	PMID:29040270
Molecular Function	GO:0005515	protein binding	PLXNB1	IPI	UniProtKB:P61587	Human	PMID:29040270
Molecular Function	GO:0005515	protein binding	PLXNB1	IPI	UniProtKB:Q92730	Human	PMID:29040270
Molecular Function	GO:0005515	protein binding	Plxnb1	IPI	UniProtKB:Q68FM7|UniProtKB:Q8R4H2	Mouse	MGI:MGI:5508282|PMID:12123608
Molecular Function	GO:0005515	protein binding	Plxnb1	IPI	UniProtKB:O09126	Mouse	MGI:MGI:5297297|PMID:22019888
Molecular Function	GO:0005515	protein binding	Plxnb1	IPI	PR:O09126	Mouse	PMID:15330859
Molecular Function	GO:0017154	semaphorin receptor activity	PLXNB1	IDA		Human	PMID:19843518
Molecular Function	GO:0017154	semaphorin receptor activity	Plxnb1	IMP		Mouse	MGI:MGI:5297297|PMID:22019888
Molecular Function	GO:0017154	semaphorin receptor activity	Plxnb1	IMP		Mouse	MGI:MGI:4413657|PMID:19788569
Cellular Component	GO:0005886	plasma membrane	PLXNB1	IDA		Human	PMID:19843518
Cellular Component	GO:0002116	semaphorin receptor complex	PLXNB1	IDA		Human	PMID:19843518
Biological Process	GO:0048675	axon extension	plxnb1a	IMP	ZFIN:ZDB-MRPHLNO-090812-1	Zfish	PMID:19059233
Biological Process	GO:0048675	axon extension	plxnb1b	IMP	ZFIN:ZDB-MRPHLNO-090812-2	Zfish	PMID:19059233
Biological Process	GO:1904862	inhibitory synapse assembly	Plxnb1	IMP		Mouse	MGI:MGI:6269924|PMID:29981480
Biological Process	GO:1904862	inhibitory synapse assembly	Plxnb1	IMP		Mouse	MGI:MGI:5498626|PMID:23699507
Biological Process	GO:0007162	negative regulation of cell adhesion	PLXNB1	IDA		Human	PMID:15218527
Biological Process	GO:0033689	negative regulation of osteoblast proliferation	Plxnb1	IMP		Mouse	MGI:MGI:5297297|PMID:22019888
Biological Process	GO:0048812	neuron projection morphogenesis	Plxnb1	IMP		Mouse	MGI:MGI:4413657|PMID:19788569
Biological Process	GO:0043931	ossification involved in bone maturation	Plxnb1	IMP		Mouse	MGI:MGI:5297297|PMID:22019888
Biological Process	GO:0050772	positive regulation of axonogenesis	Plxnb1	IGI	MGI:MGI:109244	Mouse	PMID:15330859
Biological Process	GO:0043547	positive regulation of GTPase activity	Plxnb1	IMP		Mouse	MGI:MGI:4413657|PMID:19788569
Biological Process	GO:0043547	positive regulation of GTPase activity	Plxnb1	IMP		Mouse	MGI:MGI:5297297|PMID:22019888
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	Plxnb1	IMP		Mouse	MGI:MGI:4413657|PMID:19788569
Biological Process	GO:0008360	regulation of cell shape	PLXNB1	IDA		Human	PMID:19843518
Biological Process	GO:0008360	regulation of cell shape	Plxnb1	IMP		Mouse	MGI:MGI:4413657|PMID:19788569
Biological Process	GO:0051493	regulation of cytoskeleton organization	PLXNB1	IDA		Human	PMID:19843518
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	PLXNB1	IDA		Human	PMID:15218527
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	PLXNB1	IDA		Human	PMID:19843518
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	Plxnb1	IMP		Mouse	MGI:MGI:4413657|PMID:19788569
Biological Process	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis	Plxnb1	IMP		Mouse	MGI:MGI:5297297|PMID:22019888

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern