Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLPP2
  • Mouse genes Plpp2
  • Rat genes Plpp2
  • Zfish genes plpp2a,plpp2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plpp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0106235	ceramide-1-phosphate phosphatase activity	PLPP2	IDA		Human	PMID:9705349
Molecular Function	GO:0008195	phosphatidate phosphatase activity	PLPP2	IDA		Human	PMID:16467304
Molecular Function	GO:0008195	phosphatidate phosphatase activity	PLPP2	IDA		Human	PMID:9705349
Molecular Function	GO:0005515	protein binding	PLPP2	IPI	UniProtKB:Q7Z3S9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PLPP2	IPI	UniProtKB:P41235-3	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	PLPP2	IPI	UniProtKB:P42857	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLPP2	IPI	UniProtKB:Q6UX27-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLPP2	IPI	UniProtKB:Q8N5M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLPP2	IPI	UniProtKB:Q8N609	Human	PMID:32296183
Molecular Function	GO:0042392	sphingosine-1-phosphate phosphatase activity	PLPP2	IDA		Human	PMID:9705349
Cellular Component	GO:0005901	caveola	PLPP2	IDA		Human	PMID:16467304
Cellular Component	GO:0005769	early endosome	PLPP2	IDA		Human	PMID:16467304
Cellular Component	GO:0005783	endoplasmic reticulum	PLPP2	IDA		Human	PMID:16467304
Cellular Component	GO:0016020	membrane	PLPP2	IDA		Human	PMID:9705349
Cellular Component	GO:0005886	plasma membrane	PLPP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	PLPP2	IDA		Human	PMID:16467304
Biological Process	GO:0006672	ceramide metabolic process	PLPP2	IDA		Human	PMID:9705349
Biological Process	GO:0046839	phospholipid dephosphorylation	PLPP2	IDA		Human	PMID:16467304
Biological Process	GO:0046839	phospholipid dephosphorylation	PLPP2	IDA		Human	PMID:9705349
Biological Process	GO:0006644	phospholipid metabolic process	PLPP2	IDA		Human	PMID:16467304
Biological Process	GO:0006644	phospholipid metabolic process	PLPP2	IDA		Human	PMID:9705349
Biological Process	GO:1902806	regulation of cell cycle G1/S phase transition	Plpp2	IMP		Rat	PMID:16467304|RGD:15090837
Biological Process	GO:0006670	sphingosine metabolic process	PLPP2	IDA		Human	PMID:9705349

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern