Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLEKHM2
  • Mouse genes Plekhm2
  • Rat genes Plekhm2
  • Zfish genes plekhm2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plekhm2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019894	kinesin binding	PLEKHM2	IDA		Human	PMID:15905402
Molecular Function	GO:0005515	protein binding	PLEKHM2	IPI	UniProtKB:Q56061	Human	PMID:15905402
Molecular Function	GO:0005515	protein binding	PLEKHM2	IPI	UniProtKB:P51151	Human	PMID:18787122
Molecular Function	GO:0005515	protein binding	PLEKHM2	IPI	UniProtKB:Q56061	Human	PMID:18787122
Molecular Function	GO:0005515	protein binding	PLEKHM2	IPI	UniProtKB:A0A0F6B063	Human	PMID:18996344
Molecular Function	GO:0005515	protein binding	PLEKHM2	IPI	UniProtKB:Q56061	Human	PMID:18996344
Molecular Function	GO:0005515	protein binding	PLEKHM2	IPI	UniProtKB:Q9NVJ2	Human	PMID:22172677
Molecular Function	GO:0005515	protein binding	PLEKHM2	IPI	UniProtKB:Q91YS4	Human	PMID:23519214
Molecular Function	GO:0005515	protein binding	PLEKHM2	IPI	UniProtKB:Q969J3	Human	PMID:25898167
Molecular Function	GO:0005515	protein binding	PLEKHM2	IPI	UniProtKB:Q96BM9	Human	PMID:28325809
Molecular Function	GO:0005515	protein binding	PLEKHM2	IPI	UniProtKB:Q9NVJ2	Human	PMID:28325809
Cellular Component	GO:0010008	endosome membrane	PLEKHM2	IDA		Human	PMID:18996344
Cellular Component	GO:0005765	lysosomal membrane	PLEKHM2	IDA		Human	PMID:22172677
Biological Process	GO:0007030	Golgi organization	PLEKHM2	IMP		Human	PMID:15905402
Biological Process	GO:0032418	lysosome localization	PLEKHM2	IMP		Human	PMID:22172677
Biological Process	GO:0032418	lysosome localization	PLEKHM2	IMP		Human	PMID:25898167
Biological Process	GO:0032418	lysosome localization	PLEKHM2	IDA		Human	PMID:28325809
Biological Process	GO:0042267	natural killer cell mediated cytotoxicity	PLEKHM2	IMP		Human	PMID:24088571
Biological Process	GO:0032880	regulation of protein localization	PLEKHM2	IMP		Human	PMID:18787122

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern