Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLA2G4E
  • Mouse genes Pla2g4e
  • Rat genes Pla2g4e
  • Zfish genes pla2g4f.1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pla2g4e

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016410	N-acyltransferase activity	PLA2G4E	IDA		Human	PMID:29447909
Molecular Function	GO:0016410	N-acyltransferase activity	Pla2g4e	IDA		Mouse	MGI:MGI:6414734|PMID:27399000
Molecular Function	GO:0016410	N-acyltransferase activity	Pla2g4e	IDA		Mouse	MGI:MGI:6161105|PMID:29447909
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	Pla2g4e	IDA		Mouse	MGI:MGI:6414707|PMID:24413173
Molecular Function	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	Pla2g4e	IDA		Mouse	MGI:MGI:6414707|PMID:24413173
Molecular Function	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	Pla2g4e	IDA		Mouse	MGI:MGI:6414707|PMID:24413173
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	Pla2g4e	IDA		Mouse	MGI:MGI:6414707|PMID:24413173
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	Pla2g4e	IDA		Mouse	MGI:MGI:6414707|PMID:24413173
Molecular Function	GO:0070273	phosphatidylinositol-4-phosphate binding	Pla2g4e	IDA		Mouse	MGI:MGI:6414707|PMID:24413173
Molecular Function	GO:0010314	phosphatidylinositol-5-phosphate binding	Pla2g4e	IDA		Mouse	MGI:MGI:6414707|PMID:24413173
Molecular Function	GO:0004623	phospholipase A2 activity	Pla2g4e	IDA		Mouse	PMID:15866882
Cellular Component	GO:0005737	cytoplasm	Pla2g4e	IDA		Mouse	PMID:15866882
Cellular Component	GO:0031901	early endosome membrane	Pla2g4e	IDA		Mouse	MGI:MGI:6414707|PMID:24413173
Cellular Component	GO:0031901	early endosome membrane	Pla2g4e	IDA		Mouse	MGI:MGI:6161105|PMID:29447909
Cellular Component	GO:0005765	lysosomal membrane	Pla2g4e	IDA		Mouse	MGI:MGI:6161105|PMID:29447909
Cellular Component	GO:0005886	plasma membrane	Pla2g4e	IDA		Mouse	MGI:MGI:6161105|PMID:29447909
Cellular Component	GO:0005886	plasma membrane	Pla2g4e	IDA		Mouse	MGI:MGI:6414707|PMID:24413173
Biological Process	GO:0070292	N-acylphosphatidylethanolamine metabolic process	PLA2G4E	IDA		Human	PMID:29447909
Biological Process	GO:0070292	N-acylphosphatidylethanolamine metabolic process	Pla2g4e	IDA		Mouse	MGI:MGI:6414734|PMID:27399000
Biological Process	GO:0070292	N-acylphosphatidylethanolamine metabolic process	Pla2g4e	IDA		Mouse	MGI:MGI:6161105|PMID:29447909
Biological Process	GO:2001137	positive regulation of endocytic recycling	PLA2G4E	IMP		Human	PMID:24413173
Biological Process	GO:2001137	positive regulation of endocytic recycling	Pla2g4e	IMP		Mouse	MGI:MGI:6414707|PMID:24413173

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern