Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PIM3
  • Mouse genes Pim3
  • Rat genes Pim3
  • Zfish genes pim3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pim3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PIM3	IPI	UniProtKB:Q92934	Human	PMID:17270021
Molecular Function	GO:0005515	protein binding	Pim3	IPI	UniProtKB:Q9JLY0	Mouse	MGI:MGI:5294526|PMID:21099329
Molecular Function	GO:0004674	protein serine/threonine kinase activity	PIM3	IDA		Human	PMID:18593906
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Pim3	IDA		Rat	PMID:9632723|RGD:633695
Cellular Component	GO:0005829	cytosol	PIM3	IDA		Human	GO_REF:0000052
Biological Process	GO:1904322	cellular response to forskolin	Pim3	IEP		Rat	PMID:9632723|RGD:633695
Biological Process	GO:0043066	negative regulation of apoptotic process	PIM3	IMP		Human	PMID:17270021
Biological Process	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus	Pim3	IMP		Mouse	MGI:MGI:5294526|PMID:21099329
Biological Process	GO:0046777	protein autophosphorylation	Pim3	IDA		Rat	PMID:9632723|RGD:633695
Biological Process	GO:0006468	protein phosphorylation	PIM3	IDA		Human	PMID:18593906
Biological Process	GO:0007346	regulation of mitotic cell cycle	PIM3	IMP		Human	PMID:17270021

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern