Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PIGU
  • Mouse genes Pigu
  • Rat genes Pigu
  • Zfish genes pigu
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pigu

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0034235	GPI anchor binding	PIGU	IMP		Human	PMID:12802054
Molecular Function	GO:0003923	GPI-anchor transamidase activity	pigu	IMP		Zfish	PMID:20392743
Molecular Function	GO:0005515	protein binding	PIGU	IPI	UniProtKB:Q8N6L0	Human	PMID:32296183
Cellular Component	GO:0042765	GPI-anchor transamidase complex	PIGU	IPI		Human	PMID:12802054
Cellular Component	GO:0042765	GPI-anchor transamidase complex	PIGU	IDA		Human	PMID:12802054
Cellular Component	GO:0016020	membrane	PIGU	HDA		Human	PMID:19946888
Cellular Component	GO:0005886	plasma membrane	PIGU	IDA		Human	PMID:15034568
Biological Process	GO:0016255	attachment of GPI anchor to protein	PIGU	IMP		Human	PMID:12802054
Biological Process	GO:0050976	detection of mechanical stimulus involved in sensory perception of touch	pigu	IMP	ZFIN:ZDB-GENO-100629-3	Zfish	PMID:20392743
Biological Process	GO:0006506	GPI anchor biosynthetic process	PIGU	IDA		Human	PMID:15034568
Biological Process	GO:0034394	protein localization to cell surface	pigu	IMP	ZFIN:ZDB-MRPHLNO-100629-5	Zfish	PMID:20392743
Biological Process	GO:0046425	regulation of receptor signaling pathway via JAK-STAT	PIGU	IDA		Human	PMID:15034568

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern