Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PHPT1
  • Mouse genes Phpt1
  • Rat genes Phpt1
  • Zfish genes phpt1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Phpt1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019855	calcium channel inhibitor activity	PHPT1	IDA		Human	PMID:18796614
Molecular Function	GO:0005515	protein binding	PHPT1	IPI	UniProtKB:P54253	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	PHPT1	IPI	UniProtKB:O15554	Human	PMID:18796614
Molecular Function	GO:0005515	protein binding	PHPT1	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0101006	protein histidine phosphatase activity	PHPT1	IDA		Human	PMID:16219293
Molecular Function	GO:0101006	protein histidine phosphatase activity	PHPT1	IMP		Human	PMID:18796614
Molecular Function	GO:0101006	protein histidine phosphatase activity	PHPT1	IDA		Human	PMID:19138678
Molecular Function	GO:0101006	protein histidine phosphatase activity	PHPT1	IDA		Human	PMID:20501872
Molecular Function	GO:0044325	transmembrane transporter binding	PHPT1	IPI	UniProtKB:O15554	Human	PMID:18796614
Cellular Component	GO:0005829	cytosol	PHPT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	PHPT1	IDA		Human	PMID:20501872
Cellular Component	GO:0005829	cytosol	Phpt1	IDA		Mouse	MGI:MGI:5284761|PMID:18656514
Cellular Component	GO:0070062	extracellular exosome	PHPT1	HDA		Human	PMID:19056867
Cellular Component	GO:0016604	nuclear body	PHPT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	PHPT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	PHPT1	IDA		Human	GO_REF:0000052
Biological Process	GO:2000984	negative regulation of ATP citrate synthase activity	PHPT1	IDA		Human	PMID:18656514
Biological Process	GO:0051350	negative regulation of lyase activity	PHPT1	IDA		Human	PMID:20110805
Biological Process	GO:0051350	negative regulation of lyase activity	PHPT1	IDA		Human	PMID:20501872
Biological Process	GO:0050860	negative regulation of T cell receptor signaling pathway	PHPT1	IMP		Human	PMID:18796614
Biological Process	GO:0035971	peptidyl-histidine dephosphorylation	PHPT1	IDA		Human	PMID:16219293
Biological Process	GO:0035971	peptidyl-histidine dephosphorylation	PHPT1	IDA		Human	PMID:19138678
Biological Process	GO:2000147	positive regulation of cell motility	PHPT1	IMP		Human	PMID:19344975
Biological Process	GO:2000147	positive regulation of cell motility	Phpt1	IMP		Mouse	MGI:MGI:5284749|PMID:19344975
Biological Process	GO:0006470	protein dephosphorylation	PHPT1	IDA		Human	PMID:20501872
Biological Process	GO:2000249	regulation of actin cytoskeleton reorganization	PHPT1	IMP		Human	PMID:19344975

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern