Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PHLPP2
  • Mouse genes Phlpp2
  • Rat genes Phlpp2
  • Zfish genes phlpp2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Phlpp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PHLPP2	IPI	UniProtKB:P05771-2	Human	PMID:18162466
Molecular Function	GO:0005515	protein binding	PHLPP2	IPI	UniProtKB:O14745	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	PHLPP2	IPI	UniProtKB:O14745	Human	PMID:21804599
Molecular Function	GO:0005515	protein binding	PHLPP2	IPI	UniProtKB:O14745	Human	PMID:27880917
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	Phlpp2	IDA		Rat	PMID:20089132|RGD:5131540
Cellular Component	GO:0005737	cytoplasm	PHLPP2	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005737	cytoplasm	Phlpp2	IDA		Rat	PMID:20819118|RGD:8693633
Cellular Component	GO:0005829	cytosol	PHLPP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045171	intercellular bridge	PHLPP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0072686	mitotic spindle	PHLPP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	PHLPP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0001917	photoreceptor inner segment	Phlpp2	IDA		Rat	PMID:20089132|RGD:5131540
Cellular Component	GO:0042622	photoreceptor outer segment membrane	Phlpp2	IDA		Rat	PMID:20089132|RGD:5131540
Biological Process	GO:0021766	hippocampus development	Phlpp2	IEP		Rat	PMID:20819118|RGD:8693633
Biological Process	GO:0006470	protein dephosphorylation	Phlpp2	IDA		Rat	PMID:20089132|RGD:5131540

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern