Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PGGT1B
  • Mouse genes Pggt1b
  • Rat genes Pggt1b
  • Zfish genes pggt1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pggt1b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004662	CAAX-protein geranylgeranyltransferase activity	Pggt1b	IDA		Rat	PMID:8089111|RGD:2302973
Molecular Function	GO:0004662	CAAX-protein geranylgeranyltransferase activity	Pggt1b	IDA		Rat	PMID:14609943|RGD:8554040
Molecular Function	GO:1901363	heterocyclic compound binding	Pggt1b	IDA		Rat	PMID:15248757|RGD:2302978
Molecular Function	GO:0042277	peptide binding	Pggt1b	IDA		Rat	PMID:9705207|RGD:2302975
Molecular Function	GO:0005515	protein binding	PGGT1B	IPI	UniProtKB:P49354	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	PGGT1B	IPI	UniProtKB:P49354	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Pggt1b	IPI	UniProtKB:Q04631	Rat	PMID:14609943|RGD:8554040
Molecular Function	GO:0005515	protein binding	Pggt1b	IPI	RGD:2625	Rat	PMID:15248757|RGD:2302978
Molecular Function	GO:0005515	protein binding	Pggt1b	IPI	UniProtKB:Q04631	Rat	PMID:15248757|RGD:2302978
Molecular Function	GO:0005515	protein binding	Pggt1b	IPI	UniProtKB:Q04631	Rat	PMID:15451670|RGD:8553417
Molecular Function	GO:0005515	protein binding	Pggt1b	IPI	UniProtKB:Q04631	Rat	PMID:18957540|RGD:2302981
Molecular Function	GO:0004661	protein geranylgeranyltransferase activity	PGGT1B	IDA		Human	PMID:16893176
Molecular Function	GO:0036094	small molecule binding	Pggt1b	IDA		Rat	PMID:15248757|RGD:2302978
Molecular Function	GO:0008270	zinc ion binding	Pggt1b	IDA		Rat	PMID:15248757|RGD:2302978
Molecular Function	GO:0008270	zinc ion binding	Pggt1b	IDA		Rat	PMID:14609943|RGD:8554040
Cellular Component	GO:0005953	CAAX-protein geranylgeranyltransferase complex	PGGT1B	IDA		Human	PMID:16893176
Cellular Component	GO:0005953	CAAX-protein geranylgeranyltransferase complex	Pggt1b	IDA		Rat	PMID:15248757|RGD:2302978
Cellular Component	GO:0005953	CAAX-protein geranylgeranyltransferase complex	Pggt1b	IDA		Rat	PMID:14609943|RGD:8554040
Biological Process	GO:0001955	blood vessel maturation	pggt1b	IMP	ZFIN:ZDB-MRPHLNO-130322-3	Zfish	PMID:23206891
Biological Process	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process	Pggt1b	IMP		Rat	PMID:9153192|RGD:2302974
Biological Process	GO:0045787	positive regulation of cell cycle	Pggt1b	IMP		Rat	PMID:10544242|RGD:2302976
Biological Process	GO:0008284	positive regulation of cell population proliferation	Pggt1b	IMP		Rat	PMID:10544242|RGD:2302976
Biological Process	GO:0018344	protein geranylgeranylation	PGGT1B	IDA		Human	PMID:16893176
Biological Process	GO:0018344	protein geranylgeranylation	Pggt1b	IDA		Rat	PMID:14609943|RGD:8554040
Biological Process	GO:0034097	response to cytokine	Pggt1b	IMP		Rat	PMID:9153192|RGD:2302974

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern