Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PFKFB3
  • Mouse genes Pfkfb3
  • Rat genes Pfkfb3
  • Zfish genes pfkfb3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pfkfb3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003873	6-phosphofructo-2-kinase activity	PFKFB3	IDA		Human	PMID:10077634
Molecular Function	GO:0003873	6-phosphofructo-2-kinase activity	PFKFB3	IDA		Human	PMID:17499765
Molecular Function	GO:0005515	protein binding	PFKFB3	IPI	UniProtKB:P16118	Human	PMID:32296183
Cellular Component	GO:0005654	nucleoplasm	PFKFB3	IDA		Human	GO_REF:0000052
Biological Process	GO:0007420	brain development	Pfkfb3	IEP		Rat	PMID:10648897|RGD:2302682
Biological Process	GO:0006003	fructose 2,6-bisphosphate metabolic process	Pfkfb3	IDA		Rat	PMID:17553851|RGD:2301905

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern