Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PFAS
  • Mouse genes Pfas
  • Rat genes Pfas
  • Zfish genes pfas
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pfas

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004642	phosphoribosylformylglycinamidine synthase activity	PFAS	IDA		Human	PMID:10548741
Molecular Function	GO:0004642	phosphoribosylformylglycinamidine synthase activity	PFAS	IDA		Human	PMID:27590927
Cellular Component	GO:0070062	extracellular exosome	PFAS	HDA		Human	PMID:20458337
Biological Process	GO:0044208	'de novo' AMP biosynthetic process	PFAS	IDA		Human	PMID:27590927
Biological Process	GO:0006189	'de novo' IMP biosynthetic process	PFAS	IDA		Human	PMID:27590927
Biological Process	GO:0097294	'de novo' XMP biosynthetic process	PFAS	IDA		Human	PMID:27590927
Biological Process	GO:0097065	anterior head development	Pfas	IMP	MGI:MGI:5691529	Mouse	PMID:26234751
Biological Process	GO:0097065	anterior head development	Pfas	IMP	MGI:MGI:3717451	Mouse	PMID:26234751
Biological Process	GO:0097065	anterior head development	Pfas	IMP	MGI:MGI:5476717	Mouse	PMID:26234751
Biological Process	GO:0097065	anterior head development	Pfas	IMP	MGI:MGI:5514227	Mouse	PMID:26234751
Biological Process	GO:0097065	anterior head development	Pfas	IMP	MGI:MGI:5514246	Mouse	PMID:26234751
Biological Process	GO:0097065	anterior head development	Pfas	IMP	MGI:MGI:5514248	Mouse	PMID:26234751
Biological Process	GO:0006541	glutamine metabolic process	Pfas	IDA		Rat	PMID:3436958|RGD:1599004
Biological Process	GO:0006177	GMP biosynthetic process	PFAS	IDA		Human	PMID:27590927
Biological Process	GO:0009410	response to xenobiotic stimulus	Pfas	IEP		Rat	PMID:6206692|RGD:5135300

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern