Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PDE12
  • Mouse genes Pde12
  • Rat genes Pde12
  • Zfish genes pde12
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pde12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000175	3'-5'-RNA exonuclease activity	PDE12	IMP		Human	PMID:21245038
Molecular Function	GO:0000175	3'-5'-RNA exonuclease activity	PDE12	IMP		Human	PMID:21666256
Molecular Function	GO:0004527	exonuclease activity	PDE12	IDA		Human	PMID:22285541
Molecular Function	GO:0004535	poly(A)-specific ribonuclease activity	PDE12	IMP		Human	PMID:15231837
Cellular Component	GO:0005759	mitochondrial matrix	PDE12	IMP		Human	PMID:21245038
Cellular Component	GO:0005759	mitochondrial matrix	PDE12	IDA		Human	PMID:21666256
Cellular Component	GO:0005739	mitochondrion	Pde12	HDA		Mouse	PMID:18614015
Biological Process	GO:0071359	cellular response to dsRNA	PDE12	IDA		Human	PMID:15231837
Biological Process	GO:0035457	cellular response to interferon-alpha	PDE12	IMP		Human	PMID:15231837
Biological Process	GO:0071346	cellular response to type II interferon	PDE12	IDA		Human	PMID:15231837
Biological Process	GO:0000958	mitochondrial mRNA catabolic process	PDE12	IMP		Human	PMID:21245038
Biological Process	GO:0000958	mitochondrial mRNA catabolic process	PDE12	IMP		Human	PMID:21666256
Biological Process	GO:0060548	negative regulation of cell death	PDE12	IDA		Human	PMID:15231837
Biological Process	GO:0090324	negative regulation of oxidative phosphorylation	PDE12	IMP		Human	PMID:21666256
Biological Process	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	PDE12	IMP		Human	PMID:21245038
Biological Process	GO:0090305	nucleic acid phosphodiester bond hydrolysis	PDE12	IDA		Human	PMID:22285541
Biological Process	GO:0045070	positive regulation of viral genome replication	PDE12	IMP		Human	PMID:15231837
Biological Process	GO:0044528	regulation of mitochondrial mRNA stability	PDE12	IMP		Human	PMID:21666256
Biological Process	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	PDE12	IMP		Human	PMID:21245038
Biological Process	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	PDE12	IMP		Human	PMID:21666256

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern