Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PDCD5
  • Mouse genes Pdcd5
  • Rat genes Pdcd5
  • Zfish genes pdcd5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pdcd5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0010698	acetyltransferase activator activity	PDCD5	IDA		Human	PMID:24012345
Molecular Function	GO:0048487	beta-tubulin binding	PDCD5	IPI	UniProtKB:P07437	Human	PMID:24375412
Molecular Function	GO:0008201	heparin binding	PDCD5	IDA		Human	PMID:17165023
Molecular Function	GO:0005515	protein binding	PDCD5	IPI	UniProtKB:Q9BZS1	Human	PMID:24012345
Molecular Function	GO:0005515	protein binding	PDCD5	IPI	UniProtKB:P48643	Human	PMID:24375412
Molecular Function	GO:0005515	protein binding	PDCD5	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PDCD5	IPI	UniProtKB:Q9NS91	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PDCD5	IPI	UniProtKB:Q9UPQ4-2	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	PDCD5	HDA		Human	PMID:16791210
Cellular Component	GO:0070062	extracellular exosome	PDCD5	HDA		Human	PMID:20458337
Cellular Component	GO:0005634	nucleus	PDCD5	IDA		Human	PMID:24012345
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	PDCD5	IDA		Human	PMID:24012345
Biological Process	GO:0008285	negative regulation of cell population proliferation	PDCD5	IMP		Human	PMID:16374546
Biological Process	GO:1903645	negative regulation of chaperone-mediated protein folding	PDCD5	IMP		Human	PMID:24375412
Biological Process	GO:0043065	positive regulation of apoptotic process	PDCD5	IMP		Human	PMID:9920759
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	PDCD5	IMP		Human	PMID:16374546
Biological Process	GO:0010628	positive regulation of gene expression	PDCD5	IDA		Human	PMID:24012345
Biological Process	GO:1903638	positive regulation of protein insertion into mitochondrial outer membrane	PDCD5	IMP		Human	PMID:16374546
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	PDCD5	IMP		Human	PMID:16374546

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern