Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PACS2
  • Mouse genes Pacs2
  • Rat genes Pacs2
  • Zfish genes pacs2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pacs2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PACS2	IPI	UniProtKB:Q13547	Human	PMID:29656858
Molecular Function	GO:0005515	protein binding	PACS2	IPI	UniProtKB:Q8NER1	Human	PMID:29656858
Molecular Function	GO:0005515	protein binding	PACS2	IPI	UniProtKB:Q96EB6	Human	PMID:29656858
Molecular Function	GO:0005515	protein binding	PACS2	IPI	UniProtKB:Q9Y2I8	Human	PMID:34642815
Cellular Component	GO:0005783	endoplasmic reticulum	PACS2	IDA		Human	PMID:15692563
Cellular Component	GO:0005739	mitochondrion	PACS2	IDA		Human	GO_REF:0000052
Biological Process	GO:0000045	autophagosome assembly	PACS2	IDA		Human	PMID:23455425
Biological Process	GO:0032469	endoplasmic reticulum calcium ion homeostasis	PACS2	IMP		Human	PMID:15692567
Biological Process	GO:1990456	mitochondrion-endoplasmic reticulum membrane tethering	PACS2	IMP		Human	PMID:15692567
Biological Process	GO:0034497	protein localization to phagophore assembly site	PACS2	IDA		Human	PMID:23455425
Biological Process	GO:0072659	protein localization to plasma membrane	PACS2	IMP		Human	PMID:15692563

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern