Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes OTOL1
  • Mouse genes Otol1
  • Rat genes Otol1
  • Zfish genes otol1a,otol1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Otol1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	Otol1	IDA		Mouse	MGI:MGI:6189669|PMID:29076638
Molecular Function	GO:0005509	calcium ion binding	Otol1	IDA		Mouse	MGI:MGI:5896790|PMID:21655225
Molecular Function	GO:0005509	calcium ion binding	otol1a	IDA		Zfish	PMID:29076638|ZFIN:ZDB-PUB-171028-3
Molecular Function	GO:0005515	protein binding	Otol1	IPI	UniProtKB:Q9R171|UniProtKB:Q9Z0L3	Mouse	MGI:MGI:6189434|PMID:20856818
Molecular Function	GO:0005515	protein binding	Otol1	IPI	UniProtKB:Q9Z0L3	Mouse	MGI:MGI:5896790|PMID:21655225
Cellular Component	GO:0005576	extracellular region	Otol1	IDA		Mouse	MGI:MGI:6189434|PMID:20856818
Biological Process	GO:0048840	otolith development	otol1a	IMP	ZFIN:ZDB-MRPHLNO-050707-2	Zfish	PMID:15905077
Biological Process	GO:0045299	otolith mineralization	Otol1	IDA		Mouse	MGI:MGI:6189669|PMID:29076638
Biological Process	GO:0045299	otolith mineralization	Otol1	IDA		Mouse	MGI:MGI:5896790|PMID:21655225
Biological Process	GO:0045299	otolith mineralization	Otol1	IDA		Mouse	MGI:MGI:6189500|PMID:24748133
Biological Process	GO:0045299	otolith mineralization	otol1a	IDA		Zfish	PMID:29076638|ZFIN:ZDB-PUB-171028-3
Biological Process	GO:0051259	protein complex oligomerization	otol1a	IDA		Zfish	PMID:35447266
Biological Process	GO:0051260	protein homooligomerization	Otol1	IDA		Mouse	MGI:MGI:6189434|PMID:20856818

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern