Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes OSBPL2
  • Mouse genes Osbpl2
  • Rat genes Osbpl2
  • Zfish genes osbpl2a,osbpl2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Osbpl2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015485	cholesterol binding	OSBPL2	IDA		Human	PMID:17428193
Molecular Function	GO:0120020	cholesterol transfer activity	OSBPL2	IMP		Human	PMID:30581148
Molecular Function	GO:0008526	phosphatidylinositol transfer activity	OSBPL2	IMP		Human	PMID:30581148
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	OSBPL2	IDA		Human	PMID:30581148
Molecular Function	GO:0005515	protein binding	OSBPL2	IPI	UniProtKB:Q53XM7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	OSBPL2	IPI	UniProtKB:P62306	Human	PMID:32296183
Cellular Component	GO:0005829	cytosol	OSBPL2	IDA		Human	PMID:30581148
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	OSBPL2	IDA		Human	PMID:30581148
Cellular Component	GO:0005811	lipid droplet	OSBPL2	IMP		Human	PMID:19224871
Biological Process	GO:0030301	cholesterol transport	OSBPL2	IMP		Human	PMID:30581148
Biological Process	GO:0032367	intracellular cholesterol transport	OSBPL2	IMP		Human	PMID:30581148
Biological Process	GO:0015914	phospholipid transport	OSBPL2	IMP		Human	PMID:30581148
Biological Process	GO:0007009	plasma membrane organization	OSBPL2	IMP		Human	PMID:30581148
Biological Process	GO:0051289	protein homotetramerization	OSBPL2	IDA		Human	PMID:30581148

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern