Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NUAK1
  • Mouse genes Nuak1
  • Rat genes Nuak1
  • Zfish genes nuak1a,nuak1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nuak1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0002039	p53 binding	NUAK1	IPI	UniProtKB:P04637	Human	PMID:21317932
Molecular Function	GO:0005515	protein binding	NUAK1	IPI	UniProtKB:Q93008	Human	PMID:16306228
Molecular Function	GO:0005515	protein binding	NUAK1	IPI	UniProtKB:O95835	Human	PMID:19927127
Molecular Function	GO:0005515	protein binding	NUAK1	IPI	UniProtKB:P62140	Human	PMID:20354225
Molecular Function	GO:0005515	protein binding	NUAK1	IPI	UniProtKB:P04637	Human	PMID:21317932
Molecular Function	GO:0005515	protein binding	NUAK1	IPI	UniProtKB:P38936	Human	PMID:25329316
Molecular Function	GO:0005515	protein binding	NUAK1	IPI	UniProtKB:Q9UQ35	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	NUAK1	IPI	UniProtKB:Q93008	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	NUAK1	IPI	UniProtKB:Q9UQ35	Human	PMID:32707033
Molecular Function	GO:0004674	protein serine/threonine kinase activity	NUAK1	IDA		Human	PMID:19927127
Molecular Function	GO:0004674	protein serine/threonine kinase activity	NUAK1	IDA		Human	PMID:20354225
Molecular Function	GO:0004674	protein serine/threonine kinase activity	NUAK1	IDA		Human	PMID:21317932
Cellular Component	GO:0005737	cytoplasm	NUAK1	IDA		Human	PMID:21317932
Cellular Component	GO:0001650	fibrillar center	NUAK1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0015630	microtubule cytoskeleton	NUAK1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	NUAK1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	NUAK1	IDA		Human	PMID:21317932
Biological Process	GO:0006468	protein phosphorylation	NUAK1	IDA		Human	PMID:25329316
Biological Process	GO:0030155	regulation of cell adhesion	NUAK1	IDA		Human	PMID:20354225
Biological Process	GO:2000772	regulation of cellular senescence	NUAK1	IDA		Human	PMID:19927127
Biological Process	GO:0035507	regulation of myosin-light-chain-phosphatase activity	NUAK1	IDA		Human	PMID:20354225

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern