Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NSUN4
  • Mouse genes Nsun4
  • Rat genes
  • Zfish genes nsun4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nsun4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008168	methyltransferase activity	NSUN4	IDA		Human	PMID:23022348
Molecular Function	GO:0005515	protein binding	NSUN4	IPI	UniProtKB:Q7Z6M4	Human	PMID:21531335
Molecular Function	GO:0009383	rRNA (cytosine-C5-)-methyltransferase activity	NSUN4	EXP		Human	PMID:21531335
Molecular Function	GO:0009383	rRNA (cytosine-C5-)-methyltransferase activity	NSUN4	EXP		Human	PMID:23022348
Molecular Function	GO:0070181	small ribosomal subunit rRNA binding	Nsun4	IDA		Mouse	MGI:MGI:5573024|PMID:24516400
Cellular Component	GO:0005762	mitochondrial large ribosomal subunit	NSUN4	IDA		Human	PMID:21531335
Cellular Component	GO:0005739	mitochondrion	Nsun4	IDA		Mouse	PMID:21531335
Biological Process	GO:0042256	cytosolic ribosome assembly	Nsun4	IMP		Mouse	MGI:MGI:5573024|PMID:24516400
Biological Process	GO:0070131	positive regulation of mitochondrial translation	Nsun4	IMP		Mouse	MGI:MGI:5573024|PMID:24516400
Biological Process	GO:0031167	rRNA methylation	NSUN4	IDA		Human	PMID:23022348
Biological Process	GO:0031167	rRNA methylation	Nsun4	IMP		Mouse	MGI:MGI:5573024|PMID:24516400

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern