Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NSMCE1
  • Mouse genes Nsmce1
  • Rat genes Nsmce1
  • Zfish genes nsmce1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nsmce1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	NSMCE1	IPI	UniProtKB:Q96SB8	Human	PMID:14701739
Molecular Function	GO:0005515	protein binding	NSMCE1	IPI	UniProtKB:Q96MG7	Human	PMID:18086888
Molecular Function	GO:0005515	protein binding	NSMCE1	IPI	UniProtKB:Q96SB8	Human	PMID:18086888
Molecular Function	GO:0005515	protein binding	NSMCE1	IPI	UniProtKB:Q96MG7	Human	PMID:20864041
Molecular Function	GO:0005515	protein binding	NSMCE1	IPI	UniProtKB:Q96MG7	Human	PMID:21364888
Molecular Function	GO:0005515	protein binding	NSMCE1	IPI	UniProtKB:Q96SB8	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	NSMCE1	IPI	UniProtKB:Q96MG7	Human	PMID:27427983
Molecular Function	GO:0005515	protein binding	NSMCE1	IPI	UniProtKB:Q96MG7	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	NSMCE1	IPI	UniProtKB:Q96MG7	Human	PMID:32389690
Molecular Function	GO:0046983	protein dimerization activity	NSMCE1	IDA		Human	PMID:27427983
Molecular Function	GO:0061630	ubiquitin protein ligase activity	NSMCE1	IDA		Human	PMID:20864041
Cellular Component	GO:0000775	chromosome, centromeric region	Nsmce1	IDA		Mouse	PMID:26919979
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	NSMCE1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0097431	mitotic spindle pole	Nsmce1	IDA		Mouse	PMID:26919979
Cellular Component	GO:0005654	nucleoplasm	NSMCE1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Nsmce1	IDA		Mouse	PMID:26919979
Cellular Component	GO:0030915	Smc5-Smc6 complex	NSMCE1	IDA		Human	PMID:18086888
Cellular Component	GO:0030915	Smc5-Smc6 complex	Nsmce1	IDA		Mouse	PMID:26919979
Biological Process	GO:0006974	DNA damage response	NSMCE1	IMP		Human	PMID:18086888

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern