Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NKAP
  • Mouse genes Nkap
  • Rat genes Nkap
  • Zfish genes nkap
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nkap

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	NKAP	IDA		Human	PMID:19409814
Molecular Function	GO:0031490	chromatin DNA binding	Nkap	IDA		Mouse	PMID:20610818
Molecular Function	GO:0005515	protein binding	NKAP	IPI	UniProtKB:O15379	Human	PMID:19409814
Molecular Function	GO:0005515	protein binding	NKAP	IPI	UniProtKB:Q86X95	Human	PMID:19409814
Molecular Function	GO:0005515	protein binding	NKAP	IPI	UniProtKB:O43395	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	NKAP	IPI	UniProtKB:O75400	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	NKAP	IPI	UniProtKB:Q01081	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	NKAP	IPI	UniProtKB:Q14562	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	NKAP	IPI	UniProtKB:Q9UJV9	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	NKAP	IPI	UniProtKB:Q9Y388	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	NKAP	IPI	UniProtKB:Q9UJV9	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	NKAP	IPI	UniProtKB:Q9BXS5	Human	PMID:32296183
Molecular Function	GO:0003723	RNA binding	NKAP	HDA		Human	PMID:22681889
Cellular Component	GO:0005829	cytosol	NKAP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	NKAP	IDA		Human	GO_REF:0000052
Biological Process	GO:0030851	granulocyte differentiation	Nkap	IMP	MGI:MGI:2176073,MGI:MGI:4839023	Mouse	PMID:20610818
Biological Process	GO:0071425	hematopoietic stem cell proliferation	Nkap	IMP	MGI:MGI:2176073,MGI:MGI:4839023	Mouse	PMID:20610818
Biological Process	GO:0030097	hemopoiesis	Nkap	IMP	MGI:MGI:3765313,MGI:MGI:4839023	Mouse	PMID:20610818
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	NKAP	IDA		Human	PMID:19409814
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	NKAP	IMP		Human	PMID:31587868
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Nkap	IMP	MGI:MGI:2176073,MGI:MGI:4839023	Mouse	PMID:20610818
Biological Process	GO:0046638	positive regulation of alpha-beta T cell differentiation	NKAP	IMP		Human	PMID:19409814
Biological Process	GO:0035019	somatic stem cell population maintenance	Nkap	IMP	MGI:MGI:3765313,MGI:MGI:4839023	Mouse	PMID:20610818
Biological Process	GO:0033077	T cell differentiation in thymus	Nkap	IMP	MGI:MGI:3765313,MGI:MGI:4839023	Mouse	PMID:20610818

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern