Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NECAB2
  • Mouse genes Necab2
  • Rat genes Necab2
  • Zfish genes necab2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Necab2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031687	A2A adenosine receptor binding	NECAB2	IDA		Human	PMID:17689978
Molecular Function	GO:0005515	protein binding	NECAB2	IPI	UniProtKB:P29274	Human	PMID:17689978
Molecular Function	GO:0005515	protein binding	NECAB2	IPI	UniProtKB:P29274	Human	PMID:19694902
Molecular Function	GO:0005515	protein binding	NECAB2	IPI	UniProtKB:P41594-1	Human	PMID:19694902
Molecular Function	GO:0031802	type 5 metabotropic glutamate receptor binding	NECAB2	IDA		Human	PMID:19694902
Cellular Component	GO:0005737	cytoplasm	Necab2	IDA		Rat	PMID:12044471|RGD:1302406
Cellular Component	GO:0005886	plasma membrane	NECAB2	IDA		Human	PMID:19694902
Biological Process	GO:1904021	negative regulation of G protein-coupled receptor internalization	NECAB2	IDA		Human	PMID:17689978
Biological Process	GO:0060168	positive regulation of adenosine receptor signaling pathway	NECAB2	IDA		Human	PMID:17689978
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	NECAB2	IDA		Human	PMID:19694902
Biological Process	GO:1900451	positive regulation of glutamate receptor signaling pathway	NECAB2	IDA		Human	PMID:19694902
Biological Process	GO:1905477	positive regulation of protein localization to membrane	NECAB2	IDA		Human	PMID:19694902

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern