Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NDUFA4
  • Mouse genes Ndufa4
  • Rat genes Ndufa4
  • Zfish genes ndufa4a,ndufa4b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ndufa4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	NDUFA4	IPI	UniProtKB:Q99497	Human	PMID:19822128
Molecular Function	GO:0005515	protein binding	NDUFA4	IPI	UniProtKB:Q9BUV8	Human	PMID:31536960
Molecular Function	GO:0005515	protein binding	NDUFA4	IPI	UniProtKB:Q92782-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Ndufa4	IPI	UniProtKB:Q9CQT9	Mouse	MGI:MGI:6383486|PMID:31536960
Molecular Function	GO:0044877	protein-containing complex binding	NDUFA4	IDA		Human	PMID:23209302
Cellular Component	GO:0005743	mitochondrial inner membrane	Ndufa4	HDA		Mouse	PMID:12865426
Cellular Component	GO:0005747	mitochondrial respiratory chain complex I	NDUFA4	IDA		Human	PMID:12611891
Cellular Component	GO:0005747	mitochondrial respiratory chain complex I	NDUFA4	IDA		Human	PMID:31536960
Cellular Component	GO:0005747	mitochondrial respiratory chain complex I	Ndufa4	IDA		Mouse	MGI:MGI:6383486|PMID:31536960
Cellular Component	GO:0005747	mitochondrial respiratory chain complex I	Ndufa4	IDA		Rat	PMID:30361421|RGD:13825197
Cellular Component	GO:0005751	mitochondrial respiratory chain complex IV	NDUFA4	IPI		Human	PMID:30030519
Cellular Component	GO:0005751	mitochondrial respiratory chain complex IV	NDUFA4	IDA		Human	PMID:22902835
Cellular Component	GO:0005751	mitochondrial respiratory chain complex IV	Ndufa4	IDA		Mouse	MGI:MGI:5442221|PMID:22902835
Cellular Component	GO:0005751	mitochondrial respiratory chain complex IV	Ndufa4	IDA		Rat	PMID:30361421|RGD:13825197
Cellular Component	GO:0005739	mitochondrion	NDUFA4	IDA		Human	PMID:16729965
Cellular Component	GO:0005739	mitochondrion	Ndufa4	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Ndufa4	HDA		Mouse	PMID:18614015
Biological Process	GO:1904960	positive regulation of cytochrome-c oxidase activity	NDUFA4	IMP		Human	PMID:22902835

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern