Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NCLN
  • Mouse genes Ncln
  • Rat genes Ncln
  • Zfish genes ncln
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ncln

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	NCLN	IPI	UniProtKB:Q5JPE7	Human	PMID:17261586
Molecular Function	GO:0005515	protein binding	NCLN	IPI	UniProtKB:Q5JPE7	Human	PMID:20538592
Molecular Function	GO:0005515	protein binding	NCLN	IPI	UniProtKB:Q6DGL7	Human	PMID:20538592
Molecular Function	GO:0005515	protein binding	NCLN	IPI	UniProtKB:Q9BVK8	Human	PMID:20538592
Molecular Function	GO:0005515	protein binding	NCLN	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NCLN	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NCLN	IPI	UniProtKB:P60059,UniProtKB:P60468,UniProtKB:P61619,UniProtKB:P69849,UniProtKB:Q15155,UniProtKB:Q5JPE7,UniProtKB:Q96A33,UniProtKB:Q9BVK8,UniProtKB:Q9UM00	Human	PMID:32820719
Molecular Function	GO:0043022	ribosome binding	NCLN	IDA		Human	PMID:32820719
Cellular Component	GO:0005789	endoplasmic reticulum membrane	NCLN	IDA		Human	PMID:20538592
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ncln	IDA		Zfish	PMID:15257293|ZFIN:ZDB-PUB-040719-9
Cellular Component	GO:0016020	membrane	NCLN	HDA		Human	PMID:19946888
Cellular Component	GO:0160064	multi-pass translocon complex	NCLN	IDA		Human	PMID:36261522
Cellular Component	GO:0032991	protein-containing complex	NCLN	IDA		Human	PMID:20538592
Biological Process	GO:0048484	enteric nervous system development	ncln	IMP	ZFIN:ZDB-MRPHLNO-170419-11	Zfish	PMID:28274275
Biological Process	GO:0048484	enteric nervous system development	ncln	IMP	ZFIN:ZDB-CRISPR-170419-2	Zfish	PMID:28274275
Biological Process	GO:0048484	enteric nervous system development	ncln	IMP	ZFIN:ZDB-MRPHLNO-170419-20	Zfish	PMID:28274275
Biological Process	GO:0160063	multi-pass transmembrane protein insertion into ER membrane	NCLN	IDA		Human	PMID:36261522
Biological Process	GO:1900176	negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry	ncln	IMP		Zfish	PMID:15257293|ZFIN:ZDB-PUB-040719-9
Biological Process	GO:0050821	protein stabilization	NCLN	IMP		Human	PMID:20538592
Biological Process	GO:0061635	regulation of protein complex stability	NCLN	IDA		Human	PMID:20538592
Biological Process	GO:0043254	regulation of protein-containing complex assembly	NCLN	IDA		Human	PMID:20538592
Biological Process	GO:0009966	regulation of signal transduction	ncln	IDA		Zfish	PMID:15257293
Biological Process	GO:0009966	regulation of signal transduction	ncln	IMP		Zfish	PMID:15257293

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern