Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NANOS2
  • Mouse genes Nanos2
  • Rat genes Nanos2
  • Zfish genes nanos2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nanos2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003729	mRNA binding	Nanos2	IDA		Mouse	PMID:22190708
Molecular Function	GO:0005515	protein binding	NANOS2	IPI	UniProtKB:A5YKK6	Human	PMID:24736845
Molecular Function	GO:0005515	protein binding	NANOS2	IPI	UniProtKB:O75175	Human	PMID:24736845
Molecular Function	GO:0005515	protein binding	NANOS2	IPI	UniProtKB:O95273	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NANOS2	IPI	UniProtKB:P43365	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NANOS2	IPI	UniProtKB:O95273	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	NANOS2	IPI	UniProtKB:P43365	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	NANOS2	IPI	UniProtKB:P43365	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NANOS2	IPI	UniProtKB:P60903	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Nanos2	IPI	UniProtKB:Q60809|UniProtKB:Q6ZQ08|UniProtKB:Q8K0V4|UniProtKB:Q8VEG6|UniProtKB:Q9JKY0	Mouse	MGI:MGI:4431145|PMID:20133598
Molecular Function	GO:0005515	protein binding	Nanos2	IPI	UniProtKB:Q6ZQ08	Mouse	MGI:MGI:4431145|PMID:20133598
Cellular Component	GO:0005737	cytoplasm	NANOS2	IDA		Human	PMID:19168545
Cellular Component	GO:0005737	cytoplasm	Nanos2	IDA		Mouse	MGI:MGI:4431145|PMID:20133598
Cellular Component	GO:0005634	nucleus	NANOS2	IDA		Human	PMID:22899867
Cellular Component	GO:0000932	P-body	Nanos2	IDA		Mouse	MGI:MGI:4431145|PMID:20133598
Cellular Component	GO:0048471	perinuclear region of cytoplasm	NANOS2	IDA		Human	PMID:19168545
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Nanos2	IDA		Mouse	PMID:22190708
Biological Process	GO:0044838	cell quiescence	Nanos2	IMP	MGI:MGI:2682606	Mouse	PMID:24183939
Biological Process	GO:0030718	germ-line stem cell population maintenance	Nanos2	IMP		Mouse	MGI:MGI:3776712|PMID:18281459
Biological Process	GO:0030718	germ-line stem cell population maintenance	Nanos2	IMP		Mouse	MGI:MGI:4357697|PMID:19745153
Biological Process	GO:0006402	mRNA catabolic process	Nanos2	IMP		Mouse	MGI:MGI:4431145|PMID:20133598
Biological Process	GO:0045835	negative regulation of meiotic nuclear division	Nanos2	IMP		Mouse	MGI:MGI:3776712|PMID:18281459
Biological Process	GO:0017148	negative regulation of translation	NANOS2	IDA		Human	PMID:24736845
Biological Process	GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	NANOS2	IDA		Human	PMID:24736845
Biological Process	GO:0007283	spermatogenesis	Nanos2	IMP		Mouse	MGI:MGI:4357697|PMID:19745153
Biological Process	GO:0007283	spermatogenesis	Nanos2	IMP	MGI:MGI:2682606	Mouse	PMID:12947200

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern