Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MUS81
  • Mouse genes Mus81
  • Rat genes Mus81
  • Zfish genes mus81
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mus81

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0048257	3'-flap endonuclease activity	MUS81	IMP		Human	PMID:19595721
Molecular Function	GO:0004519	endonuclease activity	MUS81	IDA		Human	PMID:19595721
Molecular Function	GO:0005515	protein binding	MUS81	IPI	UniProtKB:Q96AY2	Human	PMID:12686547
Molecular Function	GO:0005515	protein binding	MUS81	IPI	UniProtKB:A4GXA9	Human	PMID:17289582
Molecular Function	GO:0005515	protein binding	MUS81	IPI	UniProtKB:Q96AY2	Human	PMID:17289582
Molecular Function	GO:0005515	protein binding	MUS81	IPI	UniProtKB:Q96AY2	Human	PMID:19017809
Molecular Function	GO:0005515	protein binding	MUS81	IPI	UniProtKB:Q8IY92	Human	PMID:19596235
Molecular Function	GO:0005515	protein binding	MUS81	IPI	UniProtKB:Q8IY92	Human	PMID:19596236
Molecular Function	GO:0005515	protein binding	MUS81	IPI	UniProtKB:Q96AY2	Human	PMID:19596236
Molecular Function	GO:0005515	protein binding	MUS81	IPI	UniProtKB:P39748	Human	PMID:22551069
Molecular Function	GO:0005515	protein binding	MUS81	IPI	UniProtKB:Q8IY92	Human	PMID:24012755
Molecular Function	GO:0005515	protein binding	MUS81	IPI	UniProtKB:Q96AY2	Human	PMID:24733841
Molecular Function	GO:0005515	protein binding	MUS81	IPI	UniProtKB:Q8IY92	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	MUS81	IPI	UniProtKB:Q8IY92	Human	PMID:32296183
Cellular Component	GO:1905347	endodeoxyribonuclease complex	MUS81	IPI		Human	PMID:17289582
Cellular Component	GO:1905347	endodeoxyribonuclease complex	MUS81	IPI		Human	PMID:24733841
Cellular Component	GO:0005657	replication fork	MUS81	IDA		Human	PMID:28575661
Biological Process	GO:0006308	DNA catabolic process	MUS81	IMP		Human	PMID:23361013
Biological Process	GO:0006281	DNA repair	MUS81	IMP		Human	PMID:19596235
Biological Process	GO:0006302	double-strand break repair	MUS81	IDA		Human	PMID:17289582
Biological Process	GO:0006302	double-strand break repair	MUS81	IDA		Human	PMID:18413719
Biological Process	GO:0033687	osteoblast proliferation	MUS81	IMP		Human	PMID:26415217
Biological Process	GO:0031297	replication fork processing	MUS81	IDA		Human	PMID:17289582
Biological Process	GO:0031297	replication fork processing	MUS81	IDA		Human	PMID:18413719
Biological Process	GO:0072429	response to intra-S DNA damage checkpoint signaling	MUS81	IMP		Human	PMID:23361013

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern