Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MT4
  • Mouse genes Mt4
  • Rat genes Mt4
  • Zfish genes mt2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mt4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0046872	metal ion binding	Mt4	IDA		Mouse	PMID:15033980
Biological Process	GO:0001525	angiogenesis	mt2	IMP	ZFIN:ZDB-MRPHLNO-160114-2	Zfish	PMID:26198291
Biological Process	GO:0001525	angiogenesis	mt2	IMP	ZFIN:ZDB-GENO-160429-6	Zfish	PMID:26198291
Biological Process	GO:0001525	angiogenesis	mt2	IMP	ZFIN:ZDB-GENO-160429-7	Zfish	PMID:26198291
Biological Process	GO:0030003	intracellular monoatomic cation homeostasis	Mt4	IDA		Mouse	PMID:15033980
Biological Process	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	mt2	IMP	ZFIN:ZDB-MRPHLNO-160114-2	Zfish	PMID:26198291
Biological Process	GO:0010575	positive regulation of vascular endothelial growth factor production	mt2	IMP	ZFIN:ZDB-MRPHLNO-160114-2	Zfish	PMID:26198291
Biological Process	GO:0010575	positive regulation of vascular endothelial growth factor production	mt2	IMP	ZFIN:ZDB-GENO-160429-6	Zfish	PMID:26198291
Biological Process	GO:0046686	response to cadmium ion	mt2	IEP		Zfish	PMID:16799861
Biological Process	GO:0046688	response to copper ion	mt2	IDA		Zfish	PMID:18987288
Biological Process	GO:0010038	response to metal ion	mt2	IDA		Zfish	PMID:16690118
Biological Process	GO:0010038	response to metal ion	mt2	IDA		Zfish	PMID:26354112
Biological Process	GO:0010038	response to metal ion	mt2	IDA		Zfish	PMID:18987288
Biological Process	GO:0010038	response to metal ion	mt2	IDA		Zfish	PMID:15245916
Biological Process	GO:0051597	response to methylmercury	mt2	IDA		Zfish	PMID:15984772
Biological Process	GO:0010043	response to zinc ion	mt2	IDA		Zfish	PMID:18477665

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern