Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MPHOSPH8
  • Mouse genes Mphosph8
  • Rat genes Mphosph8
  • Zfish genes mphosph8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mphosph8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	MPHOSPH8	IDA		Human	PMID:29211708
Molecular Function	GO:0035064	methylated histone binding	MPHOSPH8	IDA		Human	PMID:20871592
Molecular Function	GO:0005515	protein binding	MPHOSPH8	IPI	UniProtKB:P68431	Human	PMID:20871592
Molecular Function	GO:0005515	protein binding	MPHOSPH8	IPI	UniProtKB:Q15047	Human	PMID:20871592
Molecular Function	GO:0005515	protein binding	MPHOSPH8	IPI	UniProtKB:Q9H9B1	Human	PMID:20871592
Molecular Function	GO:0005515	protein binding	MPHOSPH8	IPI	UniProtKB:Q8IVG9	Human	PMID:23532874
Molecular Function	GO:0005515	protein binding	MPHOSPH8	IPI	UniProtKB:Q15047	Human	PMID:26022416
Molecular Function	GO:0005515	protein binding	MPHOSPH8	IPI	UniProtKB:Q9UK61	Human	PMID:26022416
Molecular Function	GO:0005515	protein binding	MPHOSPH8	IPI	UniProtKB:Q9H9B1	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	MPHOSPH8	IPI	UniProtKB:Q9UK61,UniProtKB:Q9Y6X9	Human	PMID:28581500
Molecular Function	GO:0005515	protein binding	Mphosph8	IPI	UniProtKB:Q69ZR9	Mouse	PMID:31112734
Cellular Component	GO:0005737	cytoplasm	MPHOSPH8	IDA		Human	PMID:8885239
Cellular Component	GO:0005829	cytosol	MPHOSPH8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000792	heterochromatin	MPHOSPH8	IDA		Human	PMID:20871592
Cellular Component	GO:0000792	heterochromatin	MPHOSPH8	IDA		Human	PMID:28581500
Cellular Component	GO:0005730	nucleolus	MPHOSPH8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	MPHOSPH8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000786	nucleosome	MPHOSPH8	IDA		Human	PMID:20871592
Cellular Component	GO:0005634	nucleus	MPHOSPH8	IDA		Human	PMID:8885239
Cellular Component	GO:0005886	plasma membrane	MPHOSPH8	IDA		Human	GO_REF:0000052
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	MPHOSPH8	IMP		Human	PMID:20871592
Biological Process	GO:0045814	negative regulation of gene expression, epigenetic	MPHOSPH8	IDA		Human	PMID:26022416
Biological Process	GO:0045814	negative regulation of gene expression, epigenetic	MPHOSPH8	IDA		Human	PMID:28581500
Biological Process	GO:0045814	negative regulation of gene expression, epigenetic	MPHOSPH8	IDA		Human	PMID:29211708
Biological Process	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	MPHOSPH8	IMP		Human	PMID:29211708
Biological Process	GO:0090309	positive regulation of DNA methylation-dependent heterochromatin formation	MPHOSPH8	IDA		Human	PMID:28581500
Biological Process	GO:0090309	positive regulation of DNA methylation-dependent heterochromatin formation	MPHOSPH8	IDA		Human	PMID:29211708
Biological Process	GO:0044030	regulation of DNA methylation	MPHOSPH8	IMP		Human	PMID:20871592

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern