Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MORC3
  • Mouse genes Morc3
  • Rat genes Morc3
  • Zfish genes morc3a,morc3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Morc3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	MORC3	IDA		Human	PMID:34759314
Molecular Function	GO:0035064	methylated histone binding	MORC3	IDA		Human	PMID:26933034
Molecular Function	GO:0005515	protein binding	MORC3	IPI	UniProtKB:Q9NWF9	Human	PMID:32296183
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	MORC3	IDA		Human	PMID:27440897
Cellular Component	GO:0000785	chromatin	MORC3	IDA		Human	PMID:34759314
Cellular Component	GO:0005654	nucleoplasm	MORC3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	Morc3	IDA		Mouse	PMID:17332504
Cellular Component	GO:0005634	nucleus	Morc3	IDA		Mouse	PMID:17332504
Cellular Component	GO:0016605	PML body	MORC3	IDA		Human	PMID:27440897
Cellular Component	GO:0016605	PML body	MORC3	IDA		Human	PMID:17332504
Cellular Component	GO:0016605	PML body	Morc3	IDA		Mouse	PMID:17332504
Biological Process	GO:0140374	antiviral innate immune response	MORC3	IDA		Human	PMID:27440897
Biological Process	GO:0051457	maintenance of protein location in nucleus	MORC3	IDA		Human	PMID:17332504
Biological Process	GO:0051457	maintenance of protein location in nucleus	MORC3	IMP		Human	PMID:17332504
Biological Process	GO:0048147	negative regulation of fibroblast proliferation	MORC3	IDA		Human	PMID:17332504
Biological Process	GO:0032688	negative regulation of interferon-beta production	MORC3	IDA		Human	PMID:34759314
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	MORC3	IDA		Human	PMID:34759314
Biological Process	GO:0018105	peptidyl-serine phosphorylation	MORC3	IDA		Human	PMID:17332504
Biological Process	GO:2000774	positive regulation of cellular senescence	MORC3	IDA		Human	PMID:17332504
Biological Process	GO:0009791	post-embryonic development	Morc3	IMP	MGI:MGI:3765156	Mouse	PMID:17332504
Biological Process	GO:0006468	protein phosphorylation	MORC3	IDA		Human	PMID:17332504
Biological Process	GO:0050821	protein stabilization	MORC3	IDA		Human	PMID:17332504

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern