Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MIER1
  • Mouse genes Mier1
  • Rat genes Mier1
  • Zfish genes mier1a,mier1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mier1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004407	histone deacetylase activity	MIER1	IDA		Human	PMID:28046085
Molecular Function	GO:0042826	histone deacetylase binding	MIER1	IPI	UniProtKB:Q13547	Human	PMID:28046085
Molecular Function	GO:0042826	histone deacetylase binding	MIER1	IPI	UniProtKB:Q92769	Human	PMID:28046085
Molecular Function	GO:0005515	protein binding	MIER1	IPI	UniProtKB:Q13547	Human	PMID:12482978
Molecular Function	GO:0005515	protein binding	MIER1	IPI	UniProtKB:Q13547	Human	PMID:18451879
Molecular Function	GO:0005515	protein binding	MIER1	IPI	UniProtKB:Q13547	Human	PMID:21258344
Molecular Function	GO:0005515	protein binding	MIER1	IPI	UniProtKB:Q13547	Human	PMID:23752268
Molecular Function	GO:0005515	protein binding	MIER1	IPI	UniProtKB:Q13547	Human	PMID:28514442
Cellular Component	GO:0005654	nucleoplasm	MIER1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	MIER1	IDA		Human	PMID:28046085
Cellular Component	GO:0032991	protein-containing complex	MIER1	IDA		Human	PMID:28046085
Cellular Component	GO:0017053	transcription repressor complex	MIER1	IDA		Human	PMID:12482978
Biological Process	GO:0006338	chromatin remodeling	MIER1	IDA		Human	PMID:12482978
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	MIER1	HMP		Human	PMID:12761501
Biological Process	GO:0006355	regulation of DNA-templated transcription	MIER1	IDA		Human	PMID:12482978

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern