Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MICAL3
  • Mouse genes Mical3
  • Rat genes Mical3
  • Zfish genes mical3a,mical3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mical3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	MICAL3	IDA		Human	PMID:24440334
Molecular Function	GO:0060090	molecular adaptor activity	MICAL3	EXP		Human	PMID:27528609
Cellular Component	GO:0005829	cytosol	MICAL3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0090543	Flemming body	MICAL3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045171	intercellular bridge	MICAL3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	MICAL3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	MICAL3	IDA		Human	PMID:24440334
Cellular Component	GO:0005886	plasma membrane	MICAL3	IDA		Human	GO_REF:0000052
Biological Process	GO:0030042	actin filament depolymerization	MICAL3	IDA		Human	PMID:24440334
Biological Process	GO:0007010	cytoskeleton organization	MICAL3	IDA		Human	PMID:24440334
Biological Process	GO:0051179	localization	MICAL3	EXP		Human	PMID:27528609

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern