Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes METTL21C
  • Mouse genes Mettl21c
  • Rat genes Mettl21c
  • Zfish genes mettl21cb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mettl21c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031072	heat shock protein binding	METTL21C	IPI	UniProtKB:P0DMV8	Human	PMID:23349634
Molecular Function	GO:0031072	heat shock protein binding	METTL21C	IPI	UniProtKB:P0DMV9	Human	PMID:23349634
Molecular Function	GO:0005515	protein binding	METTL21C	IPI	UniProtKB:Q15369	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	METTL21C	IPI	UniProtKB:Q15369	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	METTL21C	IPI	UniProtKB:Q15369	Human	PMID:32296183
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	METTL21C	IDA		Human	PMID:22948820
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	METTL21C	IDA		Human	PMID:32611769
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	Mettl21c	IDA		Mouse	PMID:32611769
Cellular Component	GO:0005737	cytoplasm	METTL21C	IDA		Human	PMID:32611769
Cellular Component	GO:0005634	nucleus	METTL21C	IDA		Human	PMID:23349634
Cellular Component	GO:0032991	protein-containing complex	METTL21C	IDA		Human	PMID:23349634
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	Mettl21c	IMP		Mouse	PMID:24677265
Biological Process	GO:0008628	hormone-mediated apoptotic signaling pathway	Mettl21c	IMP		Mouse	PMID:24677265
Biological Process	GO:0018022	peptidyl-lysine methylation	METTL21C	IDA		Human	PMID:32611769
Biological Process	GO:0006479	protein methylation	METTL21C	IDA		Human	PMID:22948820
Biological Process	GO:0006479	protein methylation	Mettl21c	IDA		Mouse	PMID:32611769
Biological Process	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	Mettl21c	IMP		Mouse	PMID:24677265
Biological Process	GO:0007519	skeletal muscle tissue development	Mettl21c	IMP		Mouse	PMID:24677265

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern