Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MEPCE
  • Mouse genes Mepce
  • Rat genes Mepce
  • Zfish genes mepcea,mepceb,sftpbb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mepce

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0097322	7SK snRNA binding	MEPCE	IDA		Human	PMID:28431135
Molecular Function	GO:0005515	protein binding	MEPCE	IPI	UniProtKB:O94992,UniProtKB:P50750,UniProtKB:Q4G0J3	Human	PMID:30824372
Molecular Function	GO:0005515	protein binding	MEPCE	IPI	UniProtKB:Q9Y580	Human	PMID:30824372
Molecular Function	GO:1990276	RNA 5'-methyltransferase activity	MEPCE	IDA		Human	PMID:19906723
Molecular Function	GO:1990276	RNA 5'-methyltransferase activity	MEPCE	IDA		Human	PMID:28431135
Molecular Function	GO:1990276	RNA 5'-methyltransferase activity	MEPCE	IDA		Human	PMID:30559425
Molecular Function	GO:0003723	RNA binding	MEPCE	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	MEPCE	HDA		Human	PMID:22681889
Molecular Function	GO:0003723	RNA binding	MEPCE	IPI	RNAcentral:URS0000734D8F_9606	Human	PMID:30559425
Molecular Function	GO:0008173	RNA methyltransferase activity	MEPCE	IDA		Human	PMID:17643375
Molecular Function	GO:0008173	RNA methyltransferase activity	MEPCE	IMP		Human	PMID:24360279
Molecular Function	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	MEPCE	IDA		Human	PMID:17643375
Cellular Component	GO:0120259	7SK snRNP	MEPCE	IDA		Human	PMID:17643375
Cellular Component	GO:0120259	7SK snRNP	MEPCE	IDA		Human	PMID:28431135
Cellular Component	GO:0005634	nucleus	MEPCE	IDA		Human	PMID:19906723
Cellular Component	GO:0005634	nucleus	MEPCE	IDA		Human	PMID:28254838
Cellular Component	GO:1990904	ribonucleoprotein complex	MEPCE	IDA		Human	PMID:19906723
Biological Process	GO:0035562	negative regulation of chromatin binding	Mepce	IGI	MGI:MGI:107634	Mouse	PMID:23154982
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Mepce	IGI	MGI:MGI:107634	Mouse	PMID:23154982
Biological Process	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	Mepce	IMP		Mouse	PMID:23154982
Biological Process	GO:1904871	positive regulation of protein localization to Cajal body	MEPCE	IDA		Human	PMID:28254838
Biological Process	GO:1905382	positive regulation of snRNA transcription by RNA polymerase II	MEPCE	IDA		Human	PMID:28254838
Biological Process	GO:0001510	RNA methylation	MEPCE	IDA		Human	PMID:17643375
Biological Process	GO:0001510	RNA methylation	MEPCE	IDA		Human	PMID:19906723
Biological Process	GO:0001510	RNA methylation	MEPCE	IDA		Human	PMID:24360279
Biological Process	GO:0001510	RNA methylation	MEPCE	IDA		Human	PMID:28431135
Biological Process	GO:0001510	RNA methylation	MEPCE	IDA		Human	PMID:30559425
Biological Process	GO:0016073	snRNA metabolic process	MEPCE	IDA		Human	PMID:17643375
Biological Process	GO:0016073	snRNA metabolic process	MEPCE	IDA		Human	PMID:19906723
Biological Process	GO:0016073	snRNA metabolic process	MEPCE	IDA		Human	PMID:30559425
Biological Process	GO:0040031	snRNA modification	MEPCE	IDA		Human	PMID:17643375
Biological Process	GO:0040031	snRNA modification	MEPCE	IDA		Human	PMID:19906723
Biological Process	GO:0040031	snRNA modification	MEPCE	IDA		Human	PMID:24360279
Biological Process	GO:0040031	snRNA modification	MEPCE	IDA		Human	PMID:30559425

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern