Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MED11
  • Mouse genes Med11
  • Rat genes Med11
  • Zfish genes med11
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Med11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MED11	IPI	UniProtKB:Q15528	Human	PMID:12584197
Molecular Function	GO:0005515	protein binding	MED11	IPI	UniProtKB:A1L4H1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MED11	IPI	UniProtKB:P23434	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MED11	IPI	UniProtKB:Q6PIF2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MED11	IPI	UniProtKB:Q8N6Y0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MED11	IPI	UniProtKB:Q96ES7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MED11	IPI	UniProtKB:Q96HB5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MED11	IPI	UniProtKB:Q9GZM8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MED11	IPI	UniProtKB:Q9NYB9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	MED11	IPI	UniProtKB:Q9Y5B8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Med11	IPI	UniProtKB:Q15528|UniProtKB:Q9H204|UniProtKB:Q9NVC6|UniProtKB:Q9NX70	Mouse	MGI:MGI:5607368|PMID:24882805
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Med11	IDA		Rat	PMID:12584197|RGD:2304263
Cellular Component	GO:0070847	core mediator complex	MED11	IPI		Human	PMID:24882805
Cellular Component	GO:0016592	mediator complex	MED11	IDA		Human	PMID:14638676
Cellular Component	GO:0005634	nucleus	MED11	IDA		Human	PMID:24882805
Cellular Component	GO:0000151	ubiquitin ligase complex	Med11	IDA		Rat	PMID:12584197|RGD:2304263
Biological Process	GO:0016567	protein ubiquitination	Med11	IDA		Rat	PMID:12584197|RGD:2304263

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern