Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ME3
  • Mouse genes Me3
  • Rat genes Me3
  • Zfish genes me3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Me3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004473	malate dehydrogenase (decarboxylating) (NADP+) activity	ME3	IDA		Human	PMID:7818469
Molecular Function	GO:0004473	malate dehydrogenase (decarboxylating) (NADP+) activity	Me3	IDA		Mouse	PMID:25711
Molecular Function	GO:0004470	malic enzyme activity	ME3	IDA		Human	PMID:7818469
Molecular Function	GO:0070401	NADP+ binding	ME3	IDA		Human	PMID:7818469
Cellular Component	GO:0005759	mitochondrial matrix	Me3	IDA		Mouse	PMID:25711
Cellular Component	GO:0005739	mitochondrion	Me3	HDA		Mouse	PMID:18614015
Biological Process	GO:0006108	malate metabolic process	ME3	IDA		Human	PMID:7818469
Biological Process	GO:0006090	pyruvate metabolic process	ME3	IDA		Human	PMID:7818469
Biological Process	GO:0006090	pyruvate metabolic process	Me3	IDA		Mouse	PMID:25711

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern