Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MDFIC
  • Mouse genes Mdfic
  • Rat genes Mdfic
  • Zfish genes mdfi,mdfic
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mdfic

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030332	cyclin binding	MDFIC	IPI	UniProtKB:O60563	Human	PMID:12944466
Molecular Function	GO:0140297	DNA-binding transcription factor binding	MDFIC	IPI	UniProtKB:Q9UJU2	Human	PMID:12192039
Molecular Function	GO:0005515	protein binding	MDFIC	IPI	UniProtKB:O15169	Human	PMID:12192039
Molecular Function	GO:0005515	protein binding	MDFIC	IPI	UniProtKB:O60563	Human	PMID:17289077
Molecular Function	GO:0005515	protein binding	MDFIC	IPI	UniProtKB:O60583	Human	PMID:17289077
Molecular Function	GO:0005515	protein binding	Mdfic	IPI	UniProtKB:Q62520	Mouse	MGI:MGI:3056015|PMID:15465018
Molecular Function	GO:0005515	protein binding	Mdfic	IPI	UniProtKB:Q64279	Mouse	MGI:MGI:4359361|PMID:17891141
Molecular Function	GO:0005515	protein binding	Mdfic	IPI	UniProtKB:P46684|UniProtKB:Q62520|UniProtKB:Q62521	Mouse	MGI:MGI:4943413|PMID:15207726
Molecular Function	GO:0030957	Tat protein binding	MDFIC	IDA		Human	PMID:12944466
Molecular Function	GO:0030957	Tat protein binding	MDFIC	IDA		Human	PMID:16260749
Cellular Component	GO:0005737	cytoplasm	Mdfic	IDA		Mouse	MGI:MGI:4943413|PMID:15207726
Cellular Component	GO:0005730	nucleolus	Mdfic	IDA		Mouse	MGI:MGI:4359361|PMID:17891141
Cellular Component	GO:0005634	nucleus	Mdfic	IDA		Mouse	MGI:MGI:3056015|PMID:15465018
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Mdfic	IDA		Mouse	MGI:MGI:3056015|PMID:15465018
Biological Process	GO:0042308	negative regulation of protein import into nucleus	Mdfic	IDA		Mouse	MGI:MGI:4943413|PMID:15207726
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	MDFIC	IDA		Human	PMID:12944466
Biological Process	GO:0050434	positive regulation of viral transcription	MDFIC	IDA		Human	PMID:10671520
Biological Process	GO:0046328	regulation of JNK cascade	MDFIC	IDA		Human	PMID:12192039
Biological Process	GO:0030111	regulation of Wnt signaling pathway	MDFIC	IDA		Human	PMID:12192039

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern