Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MCMDC2
  • Mouse genes Mcmdc2
  • Rat genes Mcmdc2
  • Zfish genes mcmdc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mcmdc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MCMDC2	IPI	UniProtKB:Q9BS40	Human	PMID:32296183
Biological Process	GO:1990918	double-strand break repair involved in meiotic recombination	Mcmdc2	IMP	MGI:MGI:2178050,MGI:MGI:5511194	Mouse	PMID:27760146
Biological Process	GO:1990918	double-strand break repair involved in meiotic recombination	Mcmdc2	IGI	MGI:MGI:1349669	Mouse	PMID:27760146
Biological Process	GO:0042140	late meiotic recombination nodule assembly	Mcmdc2	IMP	MGI:MGI:2178050,MGI:MGI:5511194	Mouse	PMID:27760146
Biological Process	GO:0007146	meiotic recombination nodule assembly	Mcmdc2	IMP	MGI:MGI:2178050,MGI:MGI:5511194	Mouse	PMID:27760146
Biological Process	GO:0048477	oogenesis	Mcmdc2	IMP	MGI:MGI:2178050,MGI:MGI:5511194	Mouse	PMID:27760146
Biological Process	GO:0007283	spermatogenesis	Mcmdc2	IMP	MGI:MGI:2178050,MGI:MGI:5511194	Mouse	PMID:27760146
Biological Process	GO:0007130	synaptonemal complex assembly	Mcmdc2	IMP	MGI:MGI:2178050,MGI:MGI:5511194	Mouse	PMID:27760146

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern