Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MCM5
  • Mouse genes Mcm5
  • Rat genes Mcm5
  • Zfish genes mcm5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mcm5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MCM5	IPI	UniProtKB:P25205	Human	PMID:12364596
Molecular Function	GO:0005515	protein binding	MCM5	IPI	UniProtKB:P25205	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	MCM5	IPI	UniProtKB:P33993	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	MCM5	IPI	UniProtKB:P49736	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	MCM5	IPI	UniProtKB:P49736	Human	PMID:16899510
Molecular Function	GO:0005515	protein binding	MCM5	IPI	UniProtKB:P49736	Human	PMID:17296731
Molecular Function	GO:0005515	protein binding	MCM5	IPI	UniProtKB:Q9BTE3	Human	PMID:17296731
Molecular Function	GO:0005515	protein binding	MCM5	IPI	UniProtKB:O75179	Human	PMID:19150984
Molecular Function	GO:0005515	protein binding	MCM5	IPI	UniProtKB:P62805	Human	PMID:19862764
Molecular Function	GO:0005515	protein binding	MCM5	IPI	UniProtKB:Q9Y468	Human	PMID:21149733
Molecular Function	GO:0005515	protein binding	MCM5	IPI	UniProtKB:P25205	Human	PMID:22540012
Molecular Function	GO:0005515	protein binding	MCM5	IPI	UniProtKB:P49736	Human	PMID:22540012
Molecular Function	GO:0005515	protein binding	MCM5	IPI	UniProtKB:Q9BTE3	Human	PMID:22540012
Molecular Function	GO:0005515	protein binding	MCM5	IPI	UniProtKB:P33993	Human	PMID:23764002
Molecular Function	GO:0005515	protein binding	MCM5	IPI	UniProtKB:Q9BTE3	Human	PMID:24299456
Molecular Function	GO:0005515	protein binding	MCM5	IPI	UniProtKB:Q9BTE3	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	MCM5	IPI	UniProtKB:P25205	Human	PMID:28514442
Cellular Component	GO:0000781	chromosome, telomeric region	MCM5	HDA		Human	PMID:19135898
Cellular Component	GO:0071162	CMG complex	MCM5	IPI		Human	PMID:22474384
Cellular Component	GO:0042555	MCM complex	MCM5	IPI		Human	PMID:22540012
Cellular Component	GO:0042555	MCM complex	MCM5	IDA		Human	PMID:17296731
Cellular Component	GO:0016020	membrane	MCM5	HDA		Human	PMID:19946888
Cellular Component	GO:0005654	nucleoplasm	MCM5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	MCM5	IDA		Human	PMID:22474384
Biological Process	GO:0043009	chordate embryonic development	mcm5	IMP	ZFIN:ZDB-MRPHLNO-060118-1	Zfish	PMID:21358633
Biological Process	GO:0006268	DNA unwinding involved in DNA replication	MCM5	IDA		Human	PMID:22474384
Biological Process	GO:0000278	mitotic cell cycle	mcm5	IMP	ZFIN:ZDB-GENO-060112-1	Zfish	PMID:16339308
Biological Process	GO:0043066	negative regulation of apoptotic process	mcm5	IMP	ZFIN:ZDB-GENO-060112-1	Zfish	PMID:16339308

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern