Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LYPLA2
  • Mouse genes Lypla2
  • Rat genes Lypla2
  • Zfish genes lypla2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lypla2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	LYPLA2	HDA		Human	PMID:25468996
Molecular Function	GO:0004622	lysophospholipase activity	LYPLA2	IDA		Human	PMID:25301951
Molecular Function	GO:0008474	palmitoyl-(protein) hydrolase activity	LYPLA2	IDA		Human	PMID:28826475
Molecular Function	GO:0008474	palmitoyl-(protein) hydrolase activity	Lypla2	IDA		Mouse	MGI:MGI:6094388|PMID:27307232
Molecular Function	GO:0005515	protein binding	LYPLA2	IPI	UniProtKB:Q0VD86	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	LYPLA2	IDA		Human	PMID:25468996
Cellular Component	GO:0005737	cytoplasm	Lypla2	IDA		Mouse	MGI:MGI:6094388|PMID:27307232
Cellular Component	GO:0070062	extracellular exosome	LYPLA2	HDA		Human	PMID:19056867
Cellular Component	GO:0005795	Golgi stack	Lypla2	IDA		Mouse	MGI:MGI:6094388|PMID:27307232
Biological Process	GO:0046464	acylglycerol catabolic process	LYPLA2	IDA		Human	PMID:25301951
Biological Process	GO:1905344	prostaglandin catabolic process	LYPLA2	IDA		Human	PMID:25301951
Biological Process	GO:1905344	prostaglandin catabolic process	Lypla2	IDA		Mouse	MGI:MGI:6383347|PMID:25301951
Biological Process	GO:0002084	protein depalmitoylation	LYPLA2	IDA		Human	PMID:28826475
Biological Process	GO:0002084	protein depalmitoylation	Lypla2	IDA		Mouse	MGI:MGI:6094388|PMID:27307232

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern