Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LYPLA1
  • Mouse genes Lypla1
  • Rat genes LOC120099997,Lypla1
  • Zfish genes lypla1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lypla1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016298	lipase activity	LYPLA1	IDA		Human	PMID:24682756
Molecular Function	GO:0004622	lysophospholipase activity	LYPLA1	IDA		Human	PMID:19439193
Molecular Function	GO:0004622	lysophospholipase activity	LYPLA1	IDA		Human	PMID:21393252
Molecular Function	GO:0004622	lysophospholipase activity	Lypla1	IDA		Rat	PMID:9644627|RGD:633195
Molecular Function	GO:0008474	palmitoyl-(protein) hydrolase activity	LYPLA1	IDA		Human	PMID:19439193
Molecular Function	GO:0008474	palmitoyl-(protein) hydrolase activity	LYPLA1	IMP		Human	PMID:20418879
Molecular Function	GO:0008474	palmitoyl-(protein) hydrolase activity	LYPLA1	IDA		Human	PMID:32958780
Molecular Function	GO:0008474	palmitoyl-(protein) hydrolase activity	Lypla1	IDA		Mouse	MGI:MGI:6094388|PMID:27307232
Molecular Function	GO:0004620	phospholipase activity	LYPLA1	IDA		Human	PMID:21393252
Molecular Function	GO:0005515	protein binding	LYPLA1	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LYPLA1	IPI	UniProtKB:Q5VUG0	Human	PMID:32296183
Cellular Component	GO:0009986	cell surface	LYPLA1	IDA		Human	PMID:32958780
Cellular Component	GO:0005737	cytoplasm	LYPLA1	IDA		Human	PMID:19439193
Cellular Component	GO:0005829	cytosol	Lypla1	IDA		Mouse	PMID:22399288
Cellular Component	GO:0005783	endoplasmic reticulum	LYPLA1	IDA		Human	PMID:19439193
Cellular Component	GO:0070062	extracellular exosome	LYPLA1	HDA		Human	PMID:23533145
Cellular Component	GO:0005739	mitochondrion	Lypla1	HDA		Mouse	PMID:14651853
Cellular Component	GO:0031965	nuclear membrane	LYPLA1	IDA		Human	PMID:19439193
Cellular Component	GO:0005886	plasma membrane	LYPLA1	IDA		Human	PMID:19439193
Biological Process	GO:0015908	fatty acid transport	LYPLA1	IDA		Human	PMID:32958780
Biological Process	GO:0042997	negative regulation of Golgi to plasma membrane protein transport	Lypla1	IMP		Mouse	PMID:22399288
Biological Process	GO:0002084	protein depalmitoylation	LYPLA1	IDA		Human	PMID:19439193
Biological Process	GO:0002084	protein depalmitoylation	LYPLA1	IMP		Human	PMID:27481942
Biological Process	GO:0002084	protein depalmitoylation	Lypla1	IDA		Mouse	MGI:MGI:6094388|PMID:27307232
Biological Process	GO:0002084	protein depalmitoylation	Lypla1	IMP		Mouse	PMID:22399288

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern